The efficacy of Hebelys® once again demonstrated and promoted in the International Journal of Cosmetic Science
18 Septembre 2019 - 06:30PM
The efficacy of Hebelys® once again demonstrated
and promoted in the International Journal of Cosmetic Science
- New in vitro and clinical efficacy data have been
published;
- Sphingomonas hydrophobicum extract, the active substance of
Hebelys®, considerably slows down cell senescence, the main cause
of intrinsic skin ageing. It also helps to restructure the
skin;
- Thanks to its expertise in selecting appropriate biological
tests, Greentech has developed an innovative and holistic
psychobiological approach to demonstrate original properties.
- Hebelys® is receiving a positive response from the market,
which will be strengthened by the presentation of these new proofs
of effectiveness;
- The study confirms the interest and great potential of
bacterial compounds for natural and effective skin care.
DEINOVE (Euronext Growth Paris: ALDEI), a French
biotech company that uses a disruptive approach to develop
innovative antibiotics and bio-based active ingredients for
cosmetics and nutrition, announces the publication of an
article in the August issue of the International Journal of
Cosmetic Science on the benefits of the Sphingomonas hydrophobicum
extract, the active substance of Hebelys®, a cosmetic ingredient
co-developed by DEINOVE and Greentech.
The article, written jointly by Greentech and
DEINOVE entitled "Attenuation of negative effects of senescence in
human skin using an extract from Sphingomonas hydrophobicum:
development of new skin care solution", is available online:
https://doi.org/10.1111/ics.12534
It presents results from an in vitro (on
reconstructed skin) and clinical study (conducted on 24 women,
between 60 and 70 years old, over 56 days). It demonstrates the
real effectiveness of Hebelys® and provides concrete suggestions on
the mechanism of action of this innovative ingredient. The creative
positioning of biological tests, which Greentech is used to, has
revealed original properties.
The effect of Sphingomonas hydrophobicum extract
has been evaluated on cell senescence and skin isotropy1, and shows
that " Sphingomonas extract delays skin ageing process,
by reducing significantly cellular senescence, and potentiates the
mechanisms for restructuring the skin. At the same time,
Sphingomonas extract has a positive influence on self‐esteem
and general mood. "
These supplementary efficacy data enrich
Hebelys®'s sales arguments, and further boosts the positive dynamic
observed since its commercial launch.
"This publication demonstrates the clinical
benefits of Sphingomonas hydrophobicum extract, and more generally
the interest of bacterial extracts, a natural and effective
alternative to the active ingredients marketed today. It also
supports the commercial momentum of Hebelys®, distributed by our
partner Greentech. This new active, positioned on the promising
"positive aging" segment, receives good customer feedback. Several
cosmetic brands have already confirmed their interest and ordered
samples for integration into their formulations," says
Coralie MARTIN, Marketing Manager at DEINOVE.
ABOUT HEBELYS®
Hebelys® is a natural active, produced by the
fermentation of Sphingomonas, designed for mature skin.
It is the first active ingredient resulting from
the collaboration between DEINOVE and Greentech, the result of a
combination of complementary skills: DEINOVE selected the strain
from its extensive library, developed the production process to
achieve optimal fermentation performances and supervised the in
vitro tests to characterize the extract; Greentech developed the
formulation process, validated stability and safety as well as
efficacy by additional ex vivo and clinical tests.
This active ingredient has demonstrated its
ability to preserve youthful skin thanks to its action on various
ageing factors and in particular on proteins involved in the
process of cell senescence.
Marketed by Greentech, Hebelys® is designed to
be incorporated into anti-ageing, anti-wrinkle and moisturizing
products.
ABOUT DEINOVE
DEINOVE is a French biotechnology company, a
leader in disruptive innovation, which aims to help meet the
challenges of antibiotic resistance and the transition to a
sustainable production model for the cosmetics and nutrition
industries.
DEINOVE has developed a unique and comprehensive
expertise in the field of rare bacteria that it can decipher,
culture, and optimize to disclose unsuspected possibilities and
induce them to produce biobased molecules with activities of
interest on an industrial scale. To do so, DEINOVE has been
building and documenting since its creation an unparalleled
biodiversity bank that it exploits thanks to a unique technological
platform in Europe.
DEINOVE is organized around two areas of
expertise:
- ANTIBIOTICS, New-generation anti-infective
agents: A first antibiotic candidate is now in Phase II.
The Company is also pursuing the systematic exploration of
biodiversity to supply its portfolio with new leads, drawing
notably on partnerships with bioMérieux and Naicons (AGIR program
supported by Bpifrance).
- BIOACTIVES, Active ingredients of natural
origin with cosmetics as the first market and potential in
nutrition and health: DEINOVE already markets a first innovative
active ingredient, a second in partnership with Greentech, while
two others are in development with Oléos (Hallstar Group) and a
third one with DOW. It also runs a program in animal nutrition with
Groupe Avril.
Within the Euromedecine science park located in
Montpellier, DEINOVE employs 60 employees, mainly researchers,
engineers, and technicians, and has filed more than 350 patent
applications internationally. The Company has been listed on
EURONEXT GROWTH® since April 2010.
CONTACTS
InvestorsCoralie
MartinCommunication, Marketing and Investor Relations Ph.:
+33 (0)4 48 19 01 60coralie.martin@deinove.com
MediaALIZE
RPCaroline Carmagnol Tél :
+33 (0)6 64 18 99
59deinove@alizerp.com
1 Isotropy refers to the mechanical properties
of skin tissue.