FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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OMB Number: 3235-0287
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Costa Paulo F		 2. Issuer Name and Ticker or Trading Symbol

CorMedix Inc. [ CRMD ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
_____ Officer (give title below)    _____ Other (specify below)
(Last)          (First)          (Middle)

C/O CORMEDIX INC., 300 CONNELL DRIVE, SUITE 4200		 3. Date of Earliest Transaction (MM/DD/YYYY)

2/22/2022
(Street)

BERKELEY HEIGHTS, NJ 07922
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy Common Stock) $4.0300 2/22/2022  A   20000.0000     (4)2/22/2022 Common Stock 20000.0000 $0.0000 20000.0000 D 
 
Stock Option (Right to Buy Common Stock) $8.3200            (1)1/11/2031 Common Stock 20000.0000  20000.0000 D 
 
Stock Option (Right to Buy Common Stock) $4.5700            (2)9/15/2030 Common Stock 20000.0000  20000.0000 D 
 
Stock Option (Right to Buy Common Stock) $4.5700            (3)9/15/2030 Common Stock 3750.0000  3750.0000 D 
 
Explanation of Responses:
(1) These options were granted on 1/11/2021. The options are fully vested.
(2) These options were granted on 09/15/2020. One-third of the options vested on the date of grant. One-third of the options will vest on each of the first and second anniversaries of the date of grant, subject to continued service on the board.
(3) These options were granted on 09/15/2020. These options are fully vested.
(4) These options were granted on 2/22/2022. The options vest monthly with full vesting on the one year anniversary of the date of grant, subject to continued service on the board.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Costa Paulo F
C/O CORMEDIX INC.
300 CONNELL DRIVE, SUITE 4200
BERKELEY HEIGHTS, NJ 07922		X
Signatures
/s/ Paulo Costa2/23/2022
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
CorMedix (AMEX:CRMD)
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