RNS Number:5809S
Profile Therapeutics PLC
27 November 2003



Letter to:  Profile Therapeutics PLC


NOTIFICATION UNDER PART VI OF THE COMPANIES ACT 1985 (AS AMENDED BY THE
COMPANIES ACT 1989)

I write to advise that Scottish Widows Investment Management Ltd, known as
Scottish Widows Investment Partnership Ltd, no longer has a notifiable interest
in the ordinary shares of the above mentioned company.

This notification is made on behalf of Lloyds TSB Group plc, Lloyds TSB Bank
plc and Scottish Widows Group Limited.

Letter from:    Scottish Widows 
                Investment Partnership




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