Showa Denko to Launch New Shodex(TM) Analytical Columns
01 Septembre 2017 - 7:00AM
JCN Newswire (English)
Showa Denko ("SDK"; TSE:4004) will start selling next month five
new types of Shodex(TM) high-performance liquid chromatography
(HPLC) columns, namely, "GPC HK-401," "GPC HK-405" and "GPC
HK-HFIP404L" packed columns for gel permeation chromatography
(GPC*1: size exclusion chromatography [SEC*2] using organic
solvents) as well as "OHpak(TM) LB-805" packed column for gel
filtration chromatography (GFC*3: SEC using aqueous solvents) and
"IEC SP-FT 4A" packed column for ion exchange chromatography*4.
The five new analytical columns SDK developed this time feature
rapider analysis and higher sensitivity, which has been desired by
analytical column users. SDK will continue meeting our customers'
needs by developing columns which enhances accuracy of analysis of
target materials in a certain range of molecular weight, as well as
those which enable analysis of hardly-soluble polymers and rapid
analysis which is desired by users in the fields of medicine
manufacturing and biochemistry, even with general analyzers.
SDK will introduce the five new types of packed columns at JASIS
2017 exhibition (Japan Analytical & Scientific Instruments
Show) to be held at Makuhari Messe, Japan, from September 6 through
8.
1. Three new types in GPC HK Series for environment-friendly ultra
rapid analysis
GPC (organic SEC) is the most commonly used method for molecular
weight determination of polymers. On the other hand, GPC column
uses organic solvent as eluent. In 2016, aiming to realize more
environment-friendly GPC column, SDK put on the market "GPC
HK-404L" ultra rapid analytical column, which enabled us to shorten
the analysis time to one-sixth that of conventional columns and
reduce the amount of organic solvent to one-sixth. Uniform base
material particles and downsizing of column enabled GPC HK-404L to
achieve ultra rapid analysis with less environmental impact.
Furthermore, it is not necessary to use different GPC columns for
different types of solvents due to a high solvent exchangeability
of GPC HK-404L columns. No analytical device for
ultra-high-performance liquid chromatography (UHPLC) is needed
despite the rapid analysis achieved by GPC HK-404L. Thus, after the
launch, sales of GPC HK-404L have been expanding especially in the
field of analysis of polymers with molecular weight of 1 million or
less, such as polycarbonate.
1) "GPC HK-401" and "GPC HK-405" for ultra rapid analysis of
polymers with specific range of molecular weight
Following the launch of GPC HK-404L, many customers expressed their
needs for more detailed analysis of polymers with specific range of
molecular weight. To respond to these needs, SDK will launch two
new products, namely, "GPC HK-401" and "GPC HK-405." GPC HK-401 is
specialized for low molecular weight range of 100 to 1500, and
suitable for the analysis of antioxidant additives contained in
polymers. GPC HK-405 enables us to conduct ultra rapid analysis of
polymers with molecular weight range of 1 million to 2.5 million,
which is not covered by GPC HK-404L.
2) "GPC HK-HFIP404L" for rapid analysis of hardly-soluble
polymers
GPC HK-HFIP404L, which is to be marketed this time, enables us to
conduct rapid analysis of hardly-soluble polymers. Polar polymers
such as nylon and polyethylene terephthalate (PET) cannot be
dissolved in ordinary organic solvents. Therefore, analysis of
hardly-soluble polymers is usually conducted with general GPC
device and hexafluoroisopropanol (HFIP) as an eluent. However,
since HFIP is a highly expensive solvent, cost reduction in the
analysis of hardly-soluble polymers was a problem to be solved as
soon as possible. GPC HK-HFIP404L is a GPC column that enables us
to shorten the analysis time to be halved, and reduce the amount of
HFIP used in the analysis to one-sixth of that used in conventional
analysis*5. Thus, GPC HK-HFIP404L drastically reduces costs of
analysis of hardly-soluble polymers.
2. "OHpak(TM) LB-805" MALS compatible aqueous GFC column
SDK offers "OHpak(TM) Series" GFC columns, which are aqueous SEC
columns using hydrophilic polymer base as packing material.
OHpak(TM) Series have a wide variety of pore sizes to choose from,
and can analyze wide range of molecular weight. "OHpak(TM) LB-800
Series" columns, which SDK started to offer in 2015, are compatible
with MALS (multi-angle light scattering) detector that can measure
absolute molecular weight. OHpak(TM) LB-800 Series columns feature
minimum baseline noise to enable us to detect low molecular samples
which were difficult to be detected with conventional columns.
OHpak(TM) LB-800 Series columns are adopted by more and more users
centering on the pharmaceutical industry because they make it easy
for users to analyze additives to pharmaceuticals and conjugate
vaccines which comprise bound proteins and polysaccharides.
OHpak(TM) LB-805, which is to be launched this time, can take
accurate measurement of polymers with molecular weight range of 100
thousand to 1 million*6. SDK will continue expanding the lineup of
OHpak(TM) LB-800 Series columns.
3. "IEC SP-FT 4A" column for ultra rapid analysis with cation
exchange chromatography
Ion exchange chromatography is an analysis method used mainly in
the field of biochemistry to analyze proteins and nucleic acids.
SDK offers a lineup of columns for analysis of proteins and amino
acids with a wide variety of bases and functional groups to choose
from. IEC SP-FT 4A, which is to be launched this time, has a newly
developed base particle structure that enables us to shorten
analysis time to one third of that achieved by our conventional
rapid column*7. IEC SP-FT 4A enables us to conduct ultra rapid
analysis with general HPLC devices as fast as that conducted with
UHPLC. It is optimum for continuous analysis of many samples and
analysis of trace compounds.
Press release:
http://www.sdk.co.jp/english/news/2017/26789.html
Notes
*1) GPC (gel permeation chromatography): A variety of SEC, uses
organic solvents (such as tetrahydrofuran and chloroform) as
eluent.
*2) SEC (size exclusion chromatography): A form of chromatography
that uses pores of packing materials to separate and analyze sample
ingredients (such as proteins and synthesized polymers) according
to the size of molecules (molecular weight).
*3) GFC (gel filtration chromatography): Also a variety of SEC,
uses aqueous solutions as eluent.
*4) Ion exchange chromatography: A method to separate and analyze
target materials by utilizing differences in electric charges of
biomolecules such as proteins, peptides, amino acids, etc. It
elutes each ingredient by gradually changing electric property of
the eluent.
*5) Comparison with GPC HFIP-800 Series columns
*6) Comparison with OHpak(TM) LB-806 column
*7) Comparison with IEC SP-420N column
About Showa Denko K.K.
Showa Denko K.K. ("SDK"; TSE:4004, US:SHWDF) is a major
manufacturer and marketer of chemical products serving a wide range
of fields ranging from heavy industry to the electronic and
computer industries. The Petrochemicals Sector provides cracker
products such as ethylene and propylene, the Chemicals Sector
provides industrial and high-performance gases and chemicals and
high-purity gases and chemicals for the semiconductor industry, and
the Inorganics Sector provides ceramics products such as alumina,
abrasive, refractory and graphite electrodes and fine carbon
products. Today, the Aluminum Sector provides aluminum materials
and high-value-added fabricated aluminum, the Electronics Sector
provides HD media, compound semiconductors such as ultra
high-bright LEDs and rare earth magnetic alloys, and the Advanced
Battery Materials Department (ABM) provides lithium-ion battery
components. For more information, please visit
www.sdk.co.jp/english/.
Source: Showa Denko K.K.
Contact:
Public Relations Office
Phone: 81-3-5470-3235
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