Filed Pursuant to Rule 424(b)(3)
Registration No. 333-271217
PROSPECTUS
22nd Century
Group, Inc.
5,675,000 Shares of Common Stock Issuable Upon
Exercise of Warrants
This prospectus relates to the resale, from time
to time, of up to 5,675,000 shares (the “Shares”) of our common stock, $0.00001 par value per share (“Common Stock”),
by the selling stockholders identified in this prospectus under the section “Selling Stockholders” (the “Selling Stockholders”).
The Shares covered by this prospectus consist of 5,675,000 shares of Common Stock issuable upon exercise of warrants to purchase Common
Stock issued to the Selling Stockholders in a private placement as described in this propsectus (the “Warrants”).
On March 3, 2023, 22nd Century Group, Inc. (the
“Company”) consummated the closing of a private placement of Company debentures and warrants (the “Private Placement”),
pursuant to the terms and conditions of the Securities Purchase Agreement, dated March 3, 2023 (the “Securities Purchase Agreement”),
by and among the Company and certain accredited investors (the “Purchasers”). Pursuant to the Securities Purchase Agreement,
we granted certain registration rights to the Purchasers with respect to the Shares issuable upon exercise of their Warrants. The aggregate
gross proceeds to the Company from the Private Placement were approximately $20,000,000, before deducting offering expenses payable by
the Company. In connection with the Private Placement, on March 3, 2023, we also entered into a Subordinated Promissory Note and a Warrant
agreement with an existing lender (the “Lender”). See “Private Placement of Securities and Warrant.” We will not
receive any proceeds from the sale of the Shares by the Selling Stockholders under this prospectus. We will, however, receive proceeds
from any portion of the Warrants that are exercised through the payment of their respective exercise price in cash. We intend to use the
proceeds, if any, for general corporate purposes. The Selling Stockholders will bear all commissions and discounts, if any, attributable
to the sale of the Shares. We will bear all costs, expenses and fees in connection with the registration of the Shares.
The Selling Stockholders may offer such shares
from time to time as they may determine through public or private transactions or through other means described in the section entitled
“Plan of Distribution” at prevailing market prices, at prices related to prevailing market prices or at privately negotiated
prices. This prospectus does not necessarily mean that the Selling Stockholders will offer or sell the Shares. We cannot predict when
or in what amounts the Selling Stockholders may sell any of the Shares offered by this prospectus. Any shares of Common Stock subject
to resale hereunder will have been issued by us and acquired by the Selling Stockholders prior to any resale of such shares pursuant to
this prospectus.
You should read this prospectus, any prospectus
supplement and any related free writing prospectus or amendment thereto carefully, as well as any documents incorporated by reference,
before you invest in any of the securities being offered.
Our Common Stock is listed on the Nasdaq Capital
Market under the symbol “XXII.” The last reported sale price of the common stock on April 6, 2023 was $0.72 per share.
Investing in our securities involves risk. Please
read carefully the section entitled “Risk Factors” on Page 7 of this prospectus and any similar section contained in the applicable
prospectus supplement and/or other offering material concerning factors you should consider before investing in our securities which may
be offered hereby.
Neither the Securities and Exchange Commission
nor any state securities commission has approved or disapproved of these securities or determined if this prospectus is truthful or complete.
Any representation to the contrary is a criminal offense.
The date of this prospectus is April 27, 2023.
TABLE OF CONTENTS
ABOUT
THIS PROSPECTUS
This prospectus is part of a registration statement that we filed with
the U.S. Securities and Exchange Commission, or the SEC, using a “shelf” registration process. Under the shelf registration
process, the Selling Stockholders may, from time to time, offer and sell the Shares described in this prospectus in one or more offerings.
Information about the Selling Stockholders may change over time. We will not receive any of the proceeds from the sale of our Common Stock
by the Selling Stockholders under this prospectus, although we will receive proceeds from any portion of the Warrants that are exercised
through the payment of their respective exercise price in cash.
We may also file a prospectus supplement or post-effective amendment
to the registration statement of which this prospectus forms a part that may contain material information relating to these offerings.
The prospectus supplement or post-effective amendment may also add, update, or change information contained in this prospectus with respect
to that offering. If there is any inconsistency between the information in this prospectus and the applicable prospectus supplement or
post-effective amendment, you should rely on the prospectus supplement or post-effective amendment, as applicable. Before purchasing any
securities, you should carefully read this prospectus, any post-effective amendment, and any applicable prospectus supplement, together
with the additional information described under the heading “Where You Can Find More Information” and “Information
Incorporated by Reference.”
Neither we nor the Selling Stockholders have authorized anyone to provide
you with any information or to make any representations other than those contained in or incorporated by reference into this prospectus,
any post-effective amendment, or any applicable prospectus supplement prepared by or on behalf of us or to which we have referred you.
We and the Selling Stockholders take no responsibility for and can provide no assurance as to the reliability of any other information
that others may give you. The Selling Stockholders will not make an offer to sell these securities in any jurisdiction where the offer
or sale is not permitted. You should assume that the information appearing in this prospectus, any post-effective amendment and any applicable
prospectus supplement to this prospectus is accurate only as of the date on its respective cover. Our business, financial condition, results
of operations and prospects may have changed since those dates. This prospectus contains, and any post-effective amendment or any prospectus
supplement may contain, market data and industry statistics and forecasts that are based on independent industry publications and other
publicly available information. We believe this information is reliable as of the applicable date of its publication, however, we have
not independently verified the accuracy or completeness of the information included in or assumptions relied on in these third-party publications.
In addition, the market and industry data and forecasts that may be included in or incorporated by reference into this prospectus, any
post-effective amendment or any prospectus supplement may involve estimates, assumptions and other risks and uncertainties and are subject
to change based on various factors, including those discussed under the heading “Risk Factors” contained in this prospectus,
any post-effective amendment, the applicable prospectus supplement and otherwise incorporated by reference herein. Accordingly, investors
should not place undue reliance on this information.
We own or have rights to trademarks, trade names and service marks
that we use in connection with the operation of our business. In addition, ourname, logos and website name and address are our trademarks
or service marks. Solely for convenience, in some cases, the trademarks, trade names and service marks referred to in this prospectus
are listed without the applicable ®, ™ and SM symbols, but we will assert, to the fullest extent under applicable law, our rights
to these trademarks, trade names and service marks. Other trademarks, trade names and service marks appearing in this prospectus are the
property of their respective owners.
CAUTIONARY
NOTE REGARDING “FORWARD-LOOKING” INFORMATION
This registration statement and the information
incorporated by reference herein include “forward-looking statements” within the meaning of Section 27A of the Securities
Act and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). All statements, other than statements
of historical fact, included or incorporated by reference herein regarding our expectations, beliefs, plans, objectives, prospects, financial
condition, assumptions or future events are forward-looking statements. You can identify these statements by words such as “aim,”
“anticipate,” “assume,” “believe,” “could,” “due,” “estimate,”
“expect,” “goal,” “intend,” “may,” “objective,” “plan,” “potential,”
“positioned,” “predict,” “should,” “target,” “will,” “would” and
other similar expressions that are predictions of or indicate future events and future trends. These forward-looking statements are based
on current expectations, estimates, forecasts and projections about our business and the industry in which we operate and our management’s
beliefs and assumptions. These statements are not guarantees of future performance or development and involve known and unknown risks,
uncertainties and other factors that are in some cases beyond our control. All forward-looking statements are subject to risks and uncertainties
that may cause actual results to differ materially from those that we expected, including the following summary of risk factors:
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We have had a history of losses and negative cash flows, and we may be unable to achieve and sustain profitability and positive cash flows from operations. |
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Our competitors generally have, and any future competitors may have, greater financial resources and name recognition than we do, and they may therefore develop products or other technologies similar or superior to ours, or otherwise compete more successfully than we do. |
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Our research and development process may not develop marketable products, which would result in loss of our investment into such process. |
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Our ability to successfully integrate the operations of GVB Biopharma into ours and achieve the expected synergies with the acquired business. |
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We may acquire or invest in other companies, which may divert our management’s attention, result in additional dilution to our stockholders, and consume resources that are necessary to sustain our business or result in losses. |
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The coronavirus pandemic (COVID-19) or another pandemic may cause a variety of business disruptions and future business risks. |
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The failure of our information systems to function as intended or their penetration by outside parties with the intent to corrupt them could result in business disruption, litigation and regulatory action, and loss of revenue, assets, or personal or confidential data (cybersecurity). |
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We may be unsuccessful at commercializing our Very Low Nicotine Content “VLNC” tobacco as a Modified Exposure Cigarette. |
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The manufacturing of tobacco products subjects us to significant governmental regulation and the failure to comply with such regulations could have a material adverse effect on our business and subject us to substantial fines or other regulatory actions. |
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We may become subject to litigation related to cigarette smoking and/or exposure to environmental tobacco smoke, or ETS, which could severely impair our results of operations and liquidity. |
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The loss of a significant customer for whom we manufacture tobacco products could have an adverse impact on our results of operation. |
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Product liability claims, product recalls, or other claims could cause us to incur losses or damage our reputation. |
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The FDA could force the removal of our products from the U.S. market. |
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Negative press from being in the hemp/cannabis space could have a material adverse effect on our business, financial condition, and results of operations. |
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Any business-related cannabinoid production is dependent on laws pertaining to the hemp/cannabis industry. |
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Certain of our proprietary rights have expired or may expire or may not otherwise adequately protect our intellectual property, products and potential products, and if we cannot obtain adequate protection of our intellectual property, products and potential products, we may not be able to successfully market our products and potential products. |
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We license certain patent rights from third-party owners. If such owners do not properly maintain or enforce the patents underlying such licenses, our competitive position and business prospects could be harmed. |
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Our stock price may be highly volatile and could decline in value. |
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We are a named defendant in certain litigation matters, including federal securities class action lawsuits and derivative complaints; if we are unable to resolve these matters favorably, then our business, operating results and financial condition may be adversely affected. |
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Future sales of our common stock will result in dilution to our common stockholders. |
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We do not expect to declare any dividends on our common stock in the foreseeable future. |
You also should carefully review the risk factors
and cautionary statements described in the other documents we file or furnish from time to time with the SEC, including our Annual Reports
on Form 10-K, Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. The forward-looking statements included in this prospectus
and any other offering material, or in the documents incorporated by reference into this prospectus and any other offering material, are
made only as of the date of the prospectus and any other offering material or the incorporated document.
We do not assume any obligation to update any forward-looking
statements. We disclaim any intention or obligation to update or revise any forward-looking statement, whether as a result of new information,
future events or otherwise.
Prospectus Summary
The following summary highlights basic information about us, this
offering, and selected information contained elsewhere in or incorporated by reference into this prospectus supplement. This summary is
not complete and does not contain all of the information that you should consider before deciding whether to invest in our common stock.
You should review this entire prospectus supplement and the accompanying prospectus carefully, including our consolidated financial statements
and other information incorporated by reference in this prospectus supplement and the accompanying prospectus, before making an investment
decision. In addition, please read the “Risk Factors” section beginning on page 7 of this prospectus supplement.
Overview
22nd Century
Group, Inc. is a leading biotechnology company focused on utilizing advanced alkaloid plant technologies to improve health and wellness
with reduced nicotine tobacco, hemp/cannabis and hops. We use modern plant breeding technologies, including genetic engineering, gene-editing,
and molecular breeding to deliver solutions for the consumer goods and pharmaceutical industries by creating new, proprietary plants with
optimized alkaloid and flavonoid profiles as well as improved yields and valuable agronomic traits. Our mission in tobacco products is
dedicated to reduce the harms of smoking by commercializing our proprietary, very low nicotine content (“VLNC”) tobacco plants
and cigarette products. We received the first and only Food and Drug Administration (“FDA”) Modified Risk Tobacco Product
(“MRTP”) authorization of a combustible cigarette in December 2021. Beginning in April 2022, we launched our proprietary
VLN® reduced nicotine cigarettes, first through a pilot program conducted in select Circle K stores in and around
Chicago, Illinois. Following our successful pilot program, we initiated an ongoing state-by-state, region-by-region rollout strategy.
Our mission
in hemp/cannabis is to develop and monetize proprietary varieties of hemp with valuable cannabinoid and terpene profiles and other superior
agronomic traits. We are a global scale provider of cannabinoid ingredients and Active Pharmaceutical Ingredients (“API”),
as well as a contract development and manufacturing organization (“CDMO”) provider of hemp-derived consumer
products.
In hops,
our mission is to leverage our experience with tobacco and hemp/cannabis, a close hop plant relative, to accelerate the development of
proprietary specialty hop varieties with valuable traits, for potential applications in life sciences and consumer products.
We have a
significant intellectual property portfolio of issued patents and patent applications relating to both tobacco and hemp/cannabis plants
and have further resources directed towards creating and securing additional intellectual property pertaining to all three franchises.
We continue to prioritize research and development activities to achieve our strategic and investment priorities.
Our Annual Report on Form 10-K for the year
ended December 31, 2022 and the subsequent reports filed pursuant to the Exchange Act provide additional information about our business,
operations and financial condition.
Corporate Information
We are a Nevada corporation and our corporate headquarters
is located at 500 Seneca Street, Suite 507, Buffalo, New York 14204. Our telephone number is (716) 270-1523. Our internet address
is www.xxiicentury.com. We do not incorporate the information on our website into this prospectus supplement, and you should not consider
it to be a part of this prospectus supplement or the accompanying prospectus. Our web site address is included as an inactive textual
reference only.
Private Placement of Securities and Warrants (“Private Placement”)
Securities Purchase
Agreement
On
March 3, 2023, the Company entered into a Securities Purchase Agreement (the “Securities Purchase Agreement”) with each of
the purchasers party thereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”)
and JGB Collateral, LLC, a Delaware limited liability company, as collateral agent for the Purchasers (the “Agent”). Pursuant
to the Securities Purchase Agreement, the Company agreed to sell to the Purchasers (i) 7% Original Issue Discount Senior Secured Debentures
(the “Debentures”) with an aggregate principal amount of $21,052,632 and (ii) warrants to purchase up to 5,000,000 shares
of the Company’s common stock, par value $0.00001 per share (the “Common Stock”), for an exercise price of $1.275 per
share, a 50% premium to the VWAP on the closing date (the “JGB Warrants”), subject to adjustments as set forth in the JGB
Warrants, for a total purchase price of $20,000,000. The JGB Warrants are exercisable beginning on September 3, 2023 and expire on September
3, 2028. The Securities Purchase Agreement contains customary representations, warranties and covenants.
Omnia Subordinated
Promissory Note and Warrant
On
March 3, 2023, the Company executed a Subordinated Promissory Note (the “Subordinated Note”) with a principal amount of $2,864,767
in favor of Omnia Ventures, LP (the “Lender” and together with the Purchasers, the “Selling Stockholders”). The
Subordinated Note refinanced the 12% Secured Promissory Note with a principal amount of $1,000,000 dated as of October 29, 2021 payable
to the Lender and the 12% Secured Promissory Note with a principal amount of $1,500,000 dated as of January 14, 2022 payable to the Lender.
In
connection with the Subordinated Note, the Company issued to Omnia, warrants to purchase up to 675,000 shares of the Company’s Common
Stock (the “Omnia Warrant” and together with the JGB Warrants, the “Warrants”) for an exercise price of $0.855
per share, subject to adjustments as set forth in the Omnia Warrant. The Omnia Warrant is exercisable beginning on September 3, 2023 and
expires on September 3, 2028.
For
more information see the section entitled “Private Placement of Securities and Warrants.”
The Offering
| Issuer |
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22nd Century Group, Inc. |
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| Shares of Common Stock offered by the Selling Stockholders |
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Up to 5,675,000 shares (the “Shares”). |
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| Shares of Common Stock outstanding prior to this offering |
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215,704,036 shares as of March 1, 2023 |
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| Use of proceeds |
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We will not receive any proceeds from the resale of the Shares by the Selling Stockholders in this offering. We will, however, receive proceeds from any portion of the Warrants that are exercised through the payment of their respective exercise price in cash. For additional information, refer to the section entitled “Use of Proceeds.” |
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| Terms of this offering |
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The Selling Stockholders may sell, transfer or otherwise dispose of any or all of the Shares offered by this prospectus from time to time on Nasdaq or any other stock exchange, market or trading facility on which the Shares are traded, or in private transactions. Th Shares may be offered and sold or otherwise disposed of by the Selling Stockholders at fixed prices, market prices prevailing at the time of sale, prices related to prevailing market prices, or privately negotiated prices. See the section entitled “Plan of Distribution.” |
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| Risk factors |
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An investment in our common stock involves a high degree of risk. See “Risk Factors” beginning on page 7 of this prospectus, the “Risk Factors” section in our most recent Annual Report on Form 10-K and any subsequent Quarterly Reports filed on Form 10-Q, and any amendment or update thereto reflected in subsequent filings with the SEC, which are incorporated by reference herein, and other information included in this prospectus supplement, the accompanying prospectus and the documents incorporated by reference in this prospectus supplement and the accompanying prospectus for a discussion of factors you should carefully consider before deciding to invest in our common stock. |
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| Market for our common stock |
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Our Common Stock is traded on Nasdaq under the symbol “XXII.” |
RISK
FACTORS
Investing in our securities involves certain risks.
Before making an investment decision, you should carefully consider the risks and other information we include or incorporate by reference
in this prospectus and any prospectus supplement. In particular, you should consider the risk factors described under the heading “Risk
Factors” in our most recent Annual Report on Form 10-K as may be revised or supplemented by our subsequent Quarterly Reports on
Form 10-Q or Current Reports on Form 8-K, each of which are on file with the SEC and are incorporated herein by reference, and which may
be amended, supplemented or superseded from time to time by other reports we file with the SEC in the future. In addition to those risk
factors, there may be additional risks and uncertainties which are not currently known to us or that we currently deem immaterial. Our
business, financial condition or results of operations could be materially adversely affected by any of these risks. The occurrence of
any of these risks might cause you to lose all or part of your investment in the offered securities. Additional risk factors may be included
in a prospectus supplement relating to a particular offering of securities.
USE
OF PROCEEDS
All proceeds from the resale of the Shares offered
by this prospectus will belong to the Selling Stockholders. We will not receive any proceeds from the resale of the Shares by the Selling
Stockholders. We will, however, receive proceeds from any portion of the Warrants that are exercised through the payment of their respective
exercise price in cash. We intend to use the proceeds, if any, for general corporate purposes.
The Selling Stockholders will pay any underwriting
fees, discounts, selling commissions, stock transfer taxes and certain legal expenses incurred by such Selling Stockholder in disposing
of its Shares of Common Stock, and we will bear all other costs, fees and expenses incurred in effecting the registration of the securities
covered by this prospectus, including, without limitation, all registration and filing fees, Nasdaq listing fees and fees and expenses
of our counsel and our independent registered public accountants.
Private
placement of SECURITIES
JCB Private Placement
On
March 3, 2023, the Company entered into a Securities Purchase Agreement with the Purchasers, pursuant to which the Company agreed to sell
to the Purchasers (i) Debentures with an aggregate principal amount of $21,052,632 and (ii) the JGB Warrants, for a total purchase price
of $20,000,000. The Securities Purchase Agreement contains customary representations, warranties and covenants. The transactions contemplated
by the Securities Purchase Agreement were consummated on March 3, 2023.
Debentures
The
Debentures bear interest at a rate of 7% per annum, payable monthly in arrears as of the last trading day of each month and on the maturity
date. The Debentures mature on March 3, 2026. At the Company’s election, subject to certain conditions, interest can be paid in
cash, shares of the Company’s common stock, or a combination thereof. The Debentures are subject to an exit payment equal to 5%
of the original principal amount, or $1,052,632, payable on the maturity date or the date the Debentures are paid in full (the “Exit
Payment”). Any time after, March 3, 2024, the Company may irrevocably elect to redeem all of the then outstanding principal amount
of the Debentures for cash in an amount equal to the entire outstanding principal balance, including accrued and unpaid interest, the
Exit Payment and a prepayment premium in an amount equal to 3% of the outstanding principal balance as of the prepayment date (collectively,
the “Prepayment Amount”). Upon the entry into a definitive agreement that would effect a change in control (as defined in
the Debentures) of the Company, the Agent may require the Company to prepay the outstanding principal balance in an amount equal to the
Prepayment Amount. Commencing on March 3, 2024, at its option, the holder of a Debenture may require the Company to redeem 2% of the original
principal amount of the Debentures per calendar month which amount may at the Company’s election, subject to certain exceptions,
be paid in cash, shares of the Company’s common stock, or a combination thereof.
The
Debentures contain customary representations, warranties and covenants including among other things and subject to certain exceptions,
covenants that restrict the Company from incurring additional indebtedness, creating or permitting liens on assets, making or holding
any investments, repaying outstanding indebtedness, paying dividends or distributions and entering into transactions with affiliates.
In addition, the Company is required to maintain at least $7,500,000 on its balance sheet in a separate account and maintain certain quarterly
revenue targets. The number of shares of Company Common Stock issuable under the Debentures is subject to any limitations imposed by the
relevant stock exchange on which the Company’s Common Stock is traded unless shareholder approval is obtained.
The
Company’s obligations under the Debentures can be accelerated upon the occurrence of certain customary events of default. In the
event of a default and acceleration of the Company’s obligations, the Company would be required to pay the Prepayment Amount, liquidated
damages and other amounts owing in respect thereof through the date of acceleration.
JGB Warrants
The
JGB Warrants are exercisable for five years from September 3, 2023, at an exercise price of $1.275 per share, a 50% premium to the VWAP
on the closing date, subject, with certain exceptions, to adjustments in the event of stock splits, dividends, subsequent dilutive offerings
and certain fundamental transactions, as more fully described in the JGB Warrant.
The
Company is obligated to register the shares of Company Common Stock issuable upon exercise of the JGB Warrants pursuant to the terms of
the Purchase Agreement.
Omnis Private Placement
Subordinated Promissory
Note
On
March 3, 2023, the Company executed the Subordinated Note with a principal amount of $2,864,767 in favor of the Lender. The Subordinated
Note refinanced the 12% Secured Promissory Note with a principal amount of $1,000,000 dated as of October 29, 2021 payable to the Lender
and the 12% Secured Promissory Note with a principal amount of $1,500,000 dated as of January 14, 2022 payable to the Lender, which were
assumed by the Company in connection with the acquisition of GVB Biopharma.
Under
the terms of the Subordinated Note, the Company is obligated to make PIK Interest. The PIK Interest accrues at a rate of 26.5% per annum,
payable monthly. The Company is not permitted to prepay all or any portion of the outstanding balance on the Subordinated Note prior to
maturity. The Subordinated Note includes customary event of default provisions. The Subordinated Note is subordinated to the Debenture
pursuant to a Subordination Agreement between the Company, the Agent and Lender.
Warrant
In
connection with the Subordinated Note, the Company issued to Lender, the Omnia Warrant. The Omnia Warrant is exercisable beginning on
September 3, 2023 and expire on September 3, 2028, at an exercise price of $0.855 per share, subject, with certain exceptions, to adjustments
in the event of stock splits, dividends, subsequent dilutive offerings and certain fundamental transactions, as more fully described in
the Omnia Warrant.
Selling
Stockholders
This prospectus relates to the resale, from time
to time, of up to 5,675,000 shares of our Common Stock, by the Selling Stockholders listed below. The Shares covered by this prospectus
include (i) up to 675,000 shares of Common Stock issuable to the Lender upon exercise of the Omnia Warrants and (ii) up to 5,000,000 shares
of Common Stock issuable to the Purchasers upon exercise of the JGB Warrants pursuant to the Securities Purchase Agreement.
In accordance with the terms of Securities Purchase
Agreement entered into with the Purchasers, this prospectus generally covers the resale of the maximum number of shares of Common Stock
issuable pursuant to the Warrants, determined as if the Warrants were exercised, as applicable, in full as of the trading day immediately
preceding the date this registration statement was initially filed with the SEC, without regard to any limitations on exercise, as applicable,
in the Warrants. The fifth column assumes the sale of all of the Shares offered by the Selling Stockholders pursuant to this prospectus.
Under the terms of the Debentures and Warrants,
neither the Purchasers nor the Lender may be issued Shares under the Debentures or each of the Purchasers’ or Lender’s respective
Warrants to the extent such issuance would cause any of the Purchasers or the Lender, together with their respective affiliates and attribution
parties, to beneficially own a number of shares of Common Stock which would exceed 9.99% of our then outstanding Common Stock following
such exercise. The number of shares in the second column does not reflect this limitation. The Selling Stockholders may sell all, some
or none of their shares in this Offering. See “Plan of Distribution.”
The following table sets forth, as of the date
of this prospectus, the name of the Selling Stockholders, the aggregate number of shares of Common Stock beneficially owned, the aggregate
number of Shares of Common Stock that the Selling Stockholders may offer pursuant to this prospectus and the number of shares of Common
Stock beneficially owned by the Selling Stockholders after the sale of the securities offered hereby.
| Name of Selling Stockholder(1) | |
Number of Shares of Common Stock
Beneficially Owned Prior to
Offering(2) | | |
Percentage of Common Stock
Beneficially Owned Prior to Offering (3)(4) | | |
Maximum Number of Shares of Common
Stock to be Sold Pursuant to
this Prospectus(5) | | |
Number of
Shares of Common
Stock Beneficially
Owned
After Offering(3) | | |
Percentage of Common Stock
Beneficially Owned After Offering (4) | |
| JGB Capital, L.P. | |
| — | | |
| — | | |
| 375,000 | | |
| — | | |
| * | |
| JGB Capital Offshore Ltd. | |
| — | | |
| — | | |
| 1,750,000 | | |
| — | | |
| * | |
| JGB Partners, L.P. | |
| — | | |
| — | | |
| 2,875,000 | | |
| — | | |
| 1.3 | % |
| Omnia Ventures, Inc. | |
| 1,127,639 | | |
| * | | |
| 675,000 | | |
| 1,127,639 | | |
| * | |
*Less than 1%.
| (1) |
Information concerning named Selling Stockholders or future transferees, pledgees, assignees, distributees, donees or successors-in-interest of or from any such stockholder or others who later hold any Selling Stockholders’ interests will be set forth in supplements to this prospectus, absent circumstances indicating that the change is material. In addition, post-effective amendments to the registration statement of which this prospectus forms a part will be filed to disclose any material changes to the plan of distribution from the description in the final prospectus. |
| (2) |
Does not include shares issuable upon exercise of the Warrants, as the Warrants are not exercisable within 60 days of March 1, 2023. |
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|
| (3) |
Beneficial ownership is determined in accordance with the rules and regulations of the SEC. In computing the number of shares beneficially owned by a person and the percentage ownership of that person, securities that are currently convertible or exercisable into shares of our Common Stock, or convertible or exercisable into shares of our Common Stock within 60 days of March 1, 2023, are deemed outstanding. Such shares, however, are not deemed outstanding for the purposes of computing the percentage ownership of any other person. Amounts reported in the fifth column assumes that the Selling Stockholders will sell all of the Shares offered pursuant to this prospectus. |
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| (4) |
Based on 215,704,036 shares of Common Stock outstanding as of March 1, 2023. |
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| (5) |
Includes the maximum number of Shares issuable upon exercise of the Warrants, which Shares are being registered by the registration statement of which this prospectus forms a part. |
PLAN
OF DISTRIBUTION
The Selling Stockholder of the securities and any
of its pledgees, assignees and successors-in-interest may, from time to time, sell any or all of their securities covered hereby on the
Nasdaq or any other stock exchange, market or trading facility on which the securities are traded or in private transactions. These sales
may be at fixed or negotiated prices. A Selling Stockholder may use any one or more of the following methods when selling securities:
The Selling Stockholder may use any one or more
of the following methods when disposing of their shares of our Common Stock:
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ordinary brokerage transactions and transactions in which the broker-dealer solicits purchasers; |
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block trades in which the broker-dealer will attempt to sell the shares as agent, but may position and resell a portion of the block as principal to facilitate the transaction; |
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purchases by a broker-dealer as principal and resale by the broker-dealer for its account; |
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an exchange distribution in accordance with the rules of the applicable exchange; |
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privately negotiated transactions; |
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settlement of short sales; |
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in transactions through broker-dealers that agree with the Selling Stockholder to sell a specified number of such shares at a stipulated price |
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through the writing or settlement of options or other hedging transactions, whether through an options exchange or otherwise; |
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a combination of any such methods of sale; and |
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any other method permitted pursuant to applicable law. |
The Selling Stockholder may also sell securities
under Rule 144 or any other exemption from registration under the Securities Act, if available, rather than under this prospectus. Broker-dealers
engaged by the Selling Stockholder may arrange for other brokers-dealers to participate in sales. Broker-dealers may receive commissions
or discounts from the Selling Stockholder (or, if any broker-dealer acts as agent for the purchaser of securities, from the purchaser)
in amounts to be negotiated, but, except as set forth in a supplement to this prospectus, in the case of an agency transaction not in
excess of a customary brokerage commission in compliance with FINRA Rule 2121; and in the case of a principal transaction a markup
or markdown in compliance with FINRA Rule 2121.
In connection with the sale of the securities
or interests therein, the Selling Stockholder may enter into hedging transactions with broker-dealers or other financial institutions,
which may in turn engage in short sales of the securities in the course of hedging the positions they assume. The Selling Stockholder
may also sell securities short and deliver these securities to close out their short positions, or loan or pledge the securities to broker-dealers
that in turn may sell these securities. The Selling Stockholder may also enter into option or other transactions with broker-dealers
or other financial institutions or create one or more derivative securities which require the delivery to such broker-dealer or other
financial institution of securities offered by this prospectus, which securities such broker-dealer or other financial institution may
resell pursuant to this prospectus (as supplemented or amended to reflect such transaction).
The Selling Stockholder and any broker-dealers
or agents that are involved in selling the securities may be deemed to be “underwriters” within the meaning of the Securities
Act in connection with such sales. In such event, any commissions received by such broker-dealers or agents and any profit on the resale
of the securities purchased by them may be deemed to be underwriting commissions or discounts under the Securities Act. Each Selling Stockholder
has informed the Company that it does not have any written or oral agreement or understanding, directly or indirectly, with any person
to distribute the securities. The Company is required to pay certain fees and expenses incurred by the Company incident to the registration
of the securities. The Company has agreed to indemnify the Selling Stockholder against certain losses, claims, damages and liabilities,
including liabilities under the Securities Act.
We agreed to use commercially reasonable efforts
to keep the registration statement of which this prospectus forms a part effective until the earlier of (i) the expiration of the JGB
Warrants and (ii) the date that all of the JGB Warrant Shares have been disposed of by the Selling Stockholders or could be disposed of
pursuant to Rule 144 without restriction. The resale securities will be sold only through registered or licensed brokers or dealers if
required under applicable state securities laws. In addition, in certain states, the resale securities covered hereby may not be sold
unless they have been registered or qualified for sale in the applicable state or an exemption from the registration or qualification
requirement is available and is complied with.
Under applicable rules and regulations under the
Exchange Act, any person engaged in the distribution of the resale securities may not simultaneously engage in market making activities
with respect to the Common Stock for the applicable restricted period, as defined in Regulation M, prior to the commencement of the distribution.
In addition, the Selling Stockholder will be subject to applicable provisions of the Exchange Act and the rules and regulations thereunder,
including Regulation M, which may limit the timing of purchases and sales of the Common Stock by the Selling Stockholder or any other
person. We will make copies of this prospectus available to the Selling Stockholder and have informed them of the need to deliver a copy
of this prospectus to each purchaser at or prior to the time of the sale (including by compliance with Rule 172 under the Securities Act).
WHERE
YOU CAN FIND MORE INFORMATION
We file annual, quarterly and current reports,
proxy statements and other information with the SEC. The SEC maintains an internet site that contains reports, proxy and information statements
and other information regarding issuers, including ours, that file electronically with the SEC. The public can obtain any document that
we file electronically with the SEC at www.sec.gov.
INCORPORATION
BY REFERENCE
We are “incorporating by reference”
specified documents that we file with the SEC, which means:
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incorporated documents are considered part of this prospectus; |
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we are disclosing important information to you by referring you to those documents; and |
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information we file with the SEC will automatically update and supersede information contained in this prospectus. |
We incorporate by reference the documents listed
below and any future filings we make with the SEC under Section 13(a), 13(c), 14 or 15(d) of the Exchange Act (i) after
the date of the registration statement on Form S-3 filed under the Securities Act with respect to securities offered by this prospectus
and prior to the effectiveness of such registration statement and (ii) after the date of this prospectus and before the end of the
offering of the securities pursuant to this prospectus:
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Our Current Reports on Form 8-K filed with the SEC on May 18, 2022 (including the Form 8-K/A filed on July 20, 2022 and the Form 8-K/A filed on March 10, 2023), March 3, 2023, March 10, 2023, March 31, 2023, April 5, 2023 and April 21, 2023; and |
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The description of our common stock contained in or incorporated into our Registration Statement on Form 8-A, filed August 12, 2021, and any amendment or report updating that description. |
Notwithstanding the foregoing, documents or portions
thereof containing information furnished under Items 2.02 and 7.01 of any Current Report on Form 8-K, including the related exhibits under
Item 9.01, are not incorporated by reference in this prospectus. Information in this prospectus supersedes related information in the
documents listed above, and information in subsequently filed documents supersedes related information in both this prospectus and the
incorporated documents.
We will provide, without charge to you, upon written
or oral request, a copy of any or all of the documents incorporated by reference in this prospectus, other than exhibits to those documents,
unless the exhibits are specifically incorporated by reference in those documents. Requests should be directed to our principal executive
offices at:
22nd Century Group, Inc.
500 Seneca Street, Suite 507,
Buffalo, New York 14204
(716) 270-1523
You can also find these filings on our website
at www.xxiicentury.com. We are not incorporating the information on our website other than these filings into this prospectus. You should
rely only on the information contained in this prospectus (including information incorporated by reference therein) and any free writing
prospectus that we may authorize to be delivered to you. We have not authorized anyone to provide you with different information. If anyone
provides you with different or inconsistent information, you should not rely on it. You should not assume that the information in this
prospectus is accurate as of any date other than the date on the front of those documents or that any document incorporated by reference
is accurate as of any date other than its filing date. You should not consider this prospectus to be an offer or solicitation relating
to the securities in any jurisdiction in which such an offer or solicitation relating to the securities is not authorized. Furthermore,
you should not consider this prospectus to be an offer or solicitation relating to the securities if the person making the offer or solicitation
is not qualified to do so, or if it is unlawful for you to receive such an offer or solicitation.
LEGAL
MATTERS
The validity of the securities offered by this
prospectus will be passed upon for us by Greenberg Traurig, P.A. The opinion of Greenberg Traurig, P.A may be conditioned upon and may
be subject to assumptions regarding future action required to be taken by us and any underwriters, dealers or agents in connection with
the issuance of any securities.
EXPERTS
The consolidated
financial statements incorporated in this Prospectus by reference to the Annual Report on Form 10-K for the year ended December 31, 2022
have been so incorporated in reliance on the report of Freed Maxick CPAs, P.C., an independent registered public accounting firm, given
on the authority of said firm as experts in auditing and accounting.
The combined
consolidated financial statements of GVB Biopharma, which appear in the Company’s Current Report on Form 8-K/A filed with the Securities
and Exchange Commission on July 20, 2022, incorporated herein by reference have been so incorporated in reliance on the report of Armanino
LLP, an independent registered public accounting firm.
5,675,000 Shares of Common Stock Issuable Upon
Exercise of Warrants
PROSPECTUS
22nd Century (AMEX:XXII)
Graphique Historique de l'Action
De Jan 2025 à Fév 2025
22nd Century (AMEX:XXII)
Graphique Historique de l'Action
De Fév 2024 à Fév 2025
