Emisphere Technologies to Hold Annual Shareholders Meeting on May 23, 2005 TARRYTOWN, N.Y., May 13 /PRNewswire-FirstCall/ -- Emisphere Technologies, Inc. will host its annual shareholders meeting on May 23, 2005 at the Doubletree Hotel, 455 South Broadway, Tarrytown, N.Y., beginning at 10:00 a.m., Eastern Daylight Time. ON-SITE ATTENDANCE INFORMATION: For those traveling from New York City, Emisphere will provide a shuttle service from the Tarrytown train station to the Doubletree Hotel at the following times: * Pick up at Tarrytown train station at 8:45 a.m., 9:15 a.m. and 9:40 a.m. for transportation to the Doubletree Hotel * Pick up at the Doubletree Hotel at 11:20 a.m., 11:50 a.m. and 12:20 p.m. for transportation back to the Tarrytown train station Seating on the shuttles will be limited and provided on a first come, first serve basis. If you are concerned about availability, please contact Gillian Racine in investor relations at 914-785-4762 to make arrangements. Taxis will also be available at the train station. *** For those shareholders who are unable to attend the meeting, the audio proceedings will be accessible live via webcast or conference call. *** CONFERENCE CALL INFORMATION The live conference call dial-in number is: 800-299-9086 (U.S./Canada) 617-786-2903 (international) Passcode: 98424245 To access a replay of the call: 888-286-8010 (U.S./Canada) 617-801-6888 (international) Passcode: 45020121 A replay of the call will also be accessible approximately two hours following the end of the call and will be archived for one week. If accessing the audio proceedings by phone, please visit the investor relations portion of Emisphere's web site at http://www.emisphere.com/ir.asp to view the corresponding slides. WEBCAST INFORMATION To access the live broadcast via Internet in listen-only mode or the subsequently archived recording please go to the investor relations portion of the Company's web site: http://www.emisphere.com/ir.asp. A corresponding slide presentation will also be posted. Please visit the site at least five minutes prior to start time for instructions or to download any required software. About Emisphere Technologies, Inc. Emisphere Technologies, Inc. is a biopharmaceutical company pioneering the oral delivery of otherwise injectable drugs. Emisphere's business strategy is to develop oral forms of injectable drugs, either alone or with corporate partners, by applying its proprietary eligen(R) technology to those drugs or licensing its eligen(R) technology to partners who typically apply it directly to their marketed drugs. Emisphere's eligen(R) technology has enabled the oral delivery of proteins, peptides, macromolecules and charged organics. Emisphere and its partners have advanced oral formulations or prototypes of salmon calcitonin, heparin, insulin, parathyroid hormone, human growth hormone and cromolyn sodium into clinical trials. Emisphere has strategic alliances with world-leading pharmaceutical companies. For further information, please visit http://www.emisphere.com/. DATASOURCE: Emisphere Technologies, Inc. CONTACT: Gillian Racine, Investor Relations of Emisphere Technologies, Inc., +1-914-785-4762, ; Media: Dan Budwick, BMC Communications, +1-212-477-9007, ext. 14, for Emisphere Technologies, Inc. Web site: http://www.emisphere.com/ http://www.emisphere.com/ir.asp

Copyright