FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

FRIEDMAN RICHARD H 		2. Issuer Name and Ticker or Trading Symbol

BioScrip, Inc. [ BIOS ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
Chairman of the Board and CEO
(Last)          (First)          (Middle)

100 CLEARBROOK ROAD 		3. Date of Earliest Transaction (MM/DD/YYYY)

4/29/2008
(Street)

ELMSFORD, NY 10523
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, $.0001 par value   4/29/2008     A    45000.00   A $0   990668.00   D    
Common Stock, $.0001 par value                  10000.00   I   By Shares Held By Ltd Partnership   (1)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option to Purchase Common Stock   $6.52   4/29/2008     A     112500.0       4/29/2009   (2) 4/29/2018   Common Stock, $.0001 par value   112500.00   $0   112500.0   D    
Employee Stock Option   $3.46                   1/2/2008   (2) 1/2/2017   Common Stock, $.0001 par value   200000.00     200000.0   D    
Employee Stock Option (Right to Buy Common Stock)   $2.16                   10/8/2000   (3) 10/8/2009   Common Stock, $.0001 par value   207806.00     207806.0   D    
Employee Stock Option (Right to Buy Common Stock)   $2.37                   10/8/2000   (3) 10/8/2009   Common Stock, $.0001 par value   42194.00     42194.00   D    
Employee Stock Option (Right to Buy Common Stock)   $12.20                   11/28/2002   (3) 11/28/2011   Common Stock, $.0001 par value   200000.00     200000.0   D    
Employee Stock Option (Right to Buy Common Stock)   $17.80                   1/2/2003   (3) 1/2/2012   Common Stock, $.0001 par value   200000.00     200000.0   D    
Employee Stock Option (Right to Buy Common Stock)   $5.80                   1/2/2004   (3) 1/2/2013   Common Stock, $.0001 par value   200000.00     200000.0   D    
Employee Stock Option (Right to Buy Common Stock)   $7.54                   1/3/2007   (2) 1/3/2016   Common Stock, $.0001 par value   200000.00     200000.0   D    
Employee Stock Option (Right to Buy)   $7.03                   1/2/2005   (3) 1/2/2014   Common Stock, $.0001 par value   200000.00     200000.0   D    
Employee Stock Option (Right to Buy)   $6.36                   1/3/2006   (3) 1/3/2015   Common Stock, $.0001 par value   200000.00     200000.0   D    
Employee Stock Option (Right to Buy)   $7.70                   1/2/2009   (2) 1/2/2018   Common Stock, $.0001 par value   130000.00     130000.0   D    
Employee Stock Option (Right to Buy)   $7.70                   1/2/2009   (2) 1/2/2018   Common Stock, $.0001 par value   70000.00     70000.00   (4) D    

Explanation of Responses:
( 1)  Share of Common Stock are owned by the Richard Friedman Family Limited Partnership, of which Mr. Friedman is a general and limited partner. Mr. Friedman has shared voting and dispositive power with respect to these shares of Common Stock.
( 2)  Vests and becomes exercisable in three equal annual installments commencing on the first anniversary of the date of grant.
( 3)  Fully Vested
( 4)  Pursuant to the terms of the Restated Employment Agreement, dated November 29, 2006, between the reporting person and the issuer, the reporting person is entitled to receive a grant of options to purchase 200,000 shares of the issuer's common stock on the first business day of each year. On January 2, 2008 there was an insufficient number of shares remaining available for grant under the issuer's stock option plan to issue the full number of options that the reporting person was entitled to receive on such date. As a result of such shortfall the reporting person was issued options to purchase 130,000 shares. Due to certain option cancellations after January 2, 2008 additional shares became available for grant under the stock option plan and the balance of the 70,000 was issued to the reporting person on February 12, 2008.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
FRIEDMAN RICHARD H
100 CLEARBROOK ROAD
ELMSFORD, NY 10523 		X
Chairman of the Board and CEO

Signatures
/s/ Richard H. Friedman 5/1/2008
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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