Initial Statement of Beneficial Ownership (3)

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^*

Couchara Georgeann

2. Date of Event Requiring Statement (MM/DD/YYYY) 4/1/2022

3. Issuer Name and Ticker or Trading Symbol

DANAHER CORP /DE/ [DHR]

(Last) (First) (Middle)

2200 PENNSYLVANIA AVENUE NW, SUITE 800W

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director _____ 10% Owner
___X___ Officer (give title below) _____ Other (specify below)
SVP, Human Resources /

(Street)

WASHINGTON, DC 20037

(City) (State) (Zip)

5. If Amendment, Date Original Filed(MM/DD/YYYY)

6. Individual or Joint/Group Filing(Check Applicable Line)

_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	5195	D

*Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)*
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivate Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security		6. Nature of Indirect Beneficial Ownership (Instr. 5)
Employee stock option (right to buy)	2/24/2016 ⁽¹⁾	2/24/2026	Common Stock	750.0	$65.95	D
Employee stock option (right to buy)	2/24/2017 ⁽¹⁾	2/24/2027	Common Stock	1580.0	$86.08	D
Employee stock option (right to buy)	2/24/2018 ⁽¹⁾	2/24/2028	Common Stock	3710.0	$99.33	D
Employee stock option (right to buy)	2/24/2019 ⁽¹⁾	2/24/2029	Common Stock	3970.0	$113.48	D
Employee stock option (right to buy)	7/15/2019 ⁽²⁾	7/15/2029	Common Stock	11320.0	$141.11	D
Employee stock option (right to buy)	2/24/2020 ⁽¹⁾	2/24/2030	Common Stock	4460.0	$156.82	D
Employee stock option (right to buy)	2/24/2021 ⁽¹⁾	2/24/2031	Common Stock	3960.0	$223.0	D
Employee stock option (right to buy)	2/24/2022 ⁽³⁾	2/24/2032	Common Stock	6839.0	$271.56	D
Danaher Deferred Compensation Programs - Danaher Stock Fund ⁽⁴⁾	⁽⁵⁾	⁽⁵⁾	Common Stock	373.092	$0.0 ⁽⁶⁾	D

Explanation of Responses:
(1)	Date shown is grant date. Twenty percent of the options became or become exercisable on each of the first five anniversaries of the grant date.
(2)	Date shown is grant date. Fifty percent of the options became or become exercisable on each of the second and third anniversaries of the grant date.
(3)	Date shown is grant date. Fifty percent of the options become exercisable on each of the third and fourth anniversaries of the grant date.
(4)	Represents the participant's and Company contributions to the Danaher stock fund in the reporting person's account under one of the plans that form part of Danaher's deferred compensation program. The Company contributions are deemed to be invested in a number of unfunded, notional shares of Danaher common stock based on the closing price of Danaher common stock as reported on the NYSE on the date such compensation is credited.
(5)	The vesting terms and manner and form of distribution of amounts contributed or deferred under the program are based upon the provisions of the respective plan, which provisions are summarized in the latest Danaher Corporation annual meeting proxy statement on Schedule 14A as filed with the Securities and Exchange Commission.
(6)	The notional shares convert on a one-for-one basis.

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
Couchara Georgeann 2200 PENNSYLVANIA AVENUE NW SUITE 800W WASHINGTON, DC 20037			SVP, Human Resources

Signatures
/s/ James F. O'Reilly, attorney-in-fact for Georgeann Couchara		4/1/2022
^**Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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