OncoVista (OVIT.PK) Reports on Gene Expression Profiling Study in Circulating Tumor Cells (CTCs) - a Molecular Tool for Ther...
23 Novembre 2009 - 2:00PM
Business Wire
OncoVista Innovative Therapies, Inc. (Pink Sheets:OVIT),
reported that the AdnaTest BreastCancer Select & Detect kit,
manufactured by AdnaGen AG (Langenhagen, Germany), is now available
for research as well as for pay-out-of-pocket patients in the Czech
Republic and Slovakia. The research team at the Czech Academy of
Science and its spin-off company, TATAA Molecular Diagnostics, have
conducted several research efforts with the goal to prove the
capability of the CTC test to improve therapeutic decision making
in several cancers.
The team has a solid scientific, as well as entrepreneurial,
background and enjoys support from established local key opinion
leaders within the oncology community. The collaboration with the
leading national oncology centers has resulted in several ongoing
clinical research projects, many of them supervised by the team's
expert, Dr. Katarina Kolostova -- in particular, a gene expression
profiling study of 140 breast cancer patients that has shown the
potential for therapy individualization. Preliminary results from
the project illuminate the evolution of the CTCs in the peripheral
blood throughout disease progression. These findings, if
reproducible on a larger patient population, will have a
substantial impact on therapy prognostics, Dr. Kolostova says. When
established in routine diagnostics, the CTC examination will become
a kind of "real-time" biopsy, reflecting the tumor changes in time,
thus facilitating better therapeutic decisions. This will lead to
improved overall health outcomes in patients while reducing
treatment costs. The research team led by Dr. Kolostova is also
collaborating with Hoffmann-La Roche on testing the suitability of
the minimally invasive CTC test as a surrogate to tissue biopsy in
breast cancer patients who have relapsed. The ultimate goal of the
Czech TATAA Molecular Diagnostics research team is to convince the
expert community as well as the national insurance carriers in the
Czech Republic and Slovakia to reimburse the new CTC test or its
sub-indication, thus making it available to support decision making
in the treatment of the whole cancer patient community.
OncoVista Innovative Therapies, Inc., is a biopharmaceutical
company involved in the development of targeted anticancer
therapies by using tumor-associated biomarkers. In conjunction with
its subsidiary, AdnaGen AG, which is based in Langenhagen, Germany,
the Company has developed and currently markets patented diagnostic
kits in Europe for the detection of circulating tumor cells in
patients with breast, colon, ovarian and prostate cancers under the
brand name AdnaGen™. The Company has also developed research
products for the detection of steroid receptors and cancer stem
cells and has research contracts in place with major pharmaceutical
companies and recognized U.S. cancer research facilities.
OncoVista has an experienced management team specialized in the
development of targeted, anticancer drugs. OncoVista’s targeted
drug development uses the proprietary, state-of-the-art molecular
platform of AdnaGen AG. Further information on OncoVista can be
found at www.oncovista.com.
Forward-Looking Statements: A number of statements contained in
this press release are forward-looking statements within the
meaning of the Private Securities Litigation Reform Act of 1995
that involve risks and uncertainties that could cause actual
results to differ materially from those expressed or implied in the
applicable statements.
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