Walgreen Co. (WAG) agreed to buy specialty and mail-service pharmacy operations from BioScrip Inc. (BIOS) for $225 million, a deal that will give the company expanded access to new and limited-distribution drugs for HIV, cancer and organ transplants.

BioScrip's shares jumped 6.3% to $6.21 in recent trading, while Walgreen's stock rose 0.3% to $33.32.

The deal nets Walgreen 30 specialty-pharmacy locations in 16 states and the District of Columbia, mainly serving HIV, cancer and transplant patients. Walgreen will also acquire parts of BioScrip's centralized specialty-pharmacy business and traditional mail-service pharmacy business, of which it is a customer through its drugstore.com division.

The new businesses "create a strong network of support for our core drugstore business to provide specialty pharmacy solutions to our patients," Walgreen President and Chief Executive Greg Wasson said in a statement.

Walgreen, which currently operates 7,818 drugstores across the U.S. and Puerto Rico and has a market capitalization of about $29.2 billion, and other drugstore retailers are aiming to bolster pharmacy services as millions of Americans are set to gain more health-care coverage after a health-care overhaul was passed last year.

Wasson has touted the role of "community pharmacy," as Walgreen makes pharmacists more accessible by bringing them out from behind counters to address customers. Walgreen is also more tightly integrating retail clinics with pharmacy services.

Meanwhile, BioScrip plans to focus on its infusion pharmacy and home health services.

During a conference call with analysts, BioScrip President and Chief Executive Rick Smith said the deal would immediately make the company's operations more flexible, adding that gross margins after the deal closes could be in the mid-to-high 30% range. That is far above the 17.3% margin BioScrip reported for the first nine months of 2011.

Smith said the deal was the result of a strategic assessment that BioScrip launched early last year, which observers said was likely aimed at costs savings and a sharper focus on higher margin product lines.

The deal value includes $170 million in cash and BioScrip's retention of $55 million in accounts receivable and working-capital liabilities. Walgreen may pay up to an additional $60 million based on the retention of certain business tied to the deal.

Walgreen said the deal will add "modestly" to earnings in the 2013 fiscal year. According to BioScrip interim Chief Financial Officer M.J. Graves, the business being sold had revenue of $938.5 million during the first nine months of 2011.

The purchase is Walgreen's largest since it closed on a $429 million acquisition of online retailer Drugstore.com Inc. in June. In early 2010, Walgreen made its largest acquisition ever when it bought New York drugstore chain Duane Reade for about $620 million in cash and $480 million in assumed debt.

-By Matt Jarzemsky and John Kell, Dow Jones Newswires;

212-416-2240; matthew.jarzemsky@dowjones.com

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