Portola Pharmaceuticals (Nasdaq:PTLA) today announced that William Lis, chief executive officer, will present at the Morgan Stanley Global Healthcare Conference on Thursday, September 17, at 11:45 a.m. Eastern Time at the Grand Hyatt New York.

The presentation will be webcast live and available for replay from Portola's website at www.portola.com in the Investor Relations section.

About Portola Pharmaceuticals, Inc.

Portola Pharmaceuticals is a biopharmaceutical company developing product candidates that could significantly advance the fields of thrombosis and other hematologic diseases. The Company is advancing its three wholly-owned programs using novel biomarker and genetic approaches that may increase the likelihood of clinical, regulatory and commercial success of its potentially life-saving therapies. These programs include betrixaban, an oral, once-daily Factor Xa inhibitor being evaluated in the APEX Phase 3 study for prophylaxis of venous thromboembolism; andexanet alfa, a recombinant protein designed to reverse the anticoagulant effect in patients treated with an oral or injectable Factor Xa inhibitor; and cerdulatinib, a Syk/JAK inhibitor in development to treat hematologic cancers. Portola's partnered program is focused on developing selective Syk inhibitors for inflammatory conditions. For more information, visit www.portola.com and follow the Company on Twitter @Portola_Pharma.

CONTACT: Investor Contact:
         Michele Mantynen
         Portola Pharmaceuticals
         ir@portola.com
         
         Media Contact:
         Julie Normart
         W2O Group
         jnormart@w2ogroup.com
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