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| Actionnaire | Type | Détenues (Réel) | % en Circulation | Valeur Marchande | Date de Reporte |
|---|---|---|---|---|---|
| Caligan Partners, LP | Institution | 6 075 028 | 7,46% | US$ 22,60M | 2026-03-31 |
| Adage Capital Partners, L.P. | Institution | 6 029 775 | 7,41% | US$ 22,43M | 2026-03-31 |
| Adage Capital Management, L.P. | Institution | 6 029 775 | 7,41% | US$ 22,43M | 2026-03-31 |
| Atlas Diversified Master Fund, Ltd. | Institution | 5 110 373 | 6,28% | US$ 19,01M | 2026-03-31 |
| Foundation Fighting Blindness | Institution | 3 792 171 | 4,66% | US$ 14,11M | 2026-05-18 |
| Bios Equity Partners LP | Institution | 3 683 429 | 4,53% | US$ 13,70M | 2026-05-12 |
| BIOS Fund III QP, LP | Institution | 2 801 953 | 3,44% | US$ 10,42M | 2026-05-12 |
| Balyasny Asset Management L.P. | Institution | 2 718 029 | 3,34% | US$ 10,11M | 2026-03-31 |
| Millennium Management LLC | Institution | 2 630 432 | 3,23% | US$ 9,79M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 2 449 987 | 3,01% | US$ 9,11M | 2026-03-31 |
| Marshall Wace LLP | Institution | 2 313 380 | 2,84% | US$ 8,61M | 2026-03-31 |
| Boxer Capital Management, LLC | Institution | 2 250 000 | 2,76% | US$ 8,37M | 2026-03-31 |
| Mr. Cameron Gallagher | Initiés | 1 974 430 | 2,43% | US$ 7,34M | 2026-04-20 |
| ADAR1 Capital Management, LLC | Institution | 1 849 004 | 2,27% | US$ 6,88M | 2026-03-31 |
| Perceptive Life Sciences Master Fund, Ltd. | Institution | 1 835 842 | 2,26% | US$ 6,83M | 2026-03-31 |
| Perceptive Advisors LLC | Institution | 1 835 842 | 2,26% | US$ 6,83M | 2026-03-31 |
| Nantahala Capital Management, LLC | Institution | 1 681 330 | 2,07% | US$ 6,25M | 2026-03-31 |
| Woodline Partners LP | Institution | 1 354 030 | 1,66% | US$ 5,04M | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 1 189 113 | 1,46% | US$ 4,42M | 2026-03-31 |
| Opaleye Management Inc. | Institution | 1 120 000 | 1,38% | US$ 4,17M | 2026-03-31 |
| Farallon Capital Management, L.L.C. | Institution | 1 000 000 | 1,23% | US$ 3,72M | 2026-03-31 |
| Dr. George Magrath | Initiés | 839 910 | 1,03% | US$ 3,12M | 2026-04-23 |
| Susquehanna International Group, LLP | Institution | 823 383 | 1,01% | US$ 3,06M | 2026-03-31 |
| Bleichroeder LP | Institution | 736 842 | 0,91% | US$ 2,74M | 2026-03-31 |
| Dr. Benjamin Yerxa | Initiés | 711 535 | 0,87% | US$ 2,65M | 2026-04-23 |
| Mr. Robert Gagnon | Initiés | 592 158 | 0,73% | US$ 2,20M | 2026-04-23 |
| Mink Brook Asset Management LLC | Institution | 590 552 | 0,73% | US$ 2,20M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 538 347 | 0,66% | US$ 2,00M | 2026-03-31 |
| Trails Edge Capital Partners, LP | Institution | 500 000 | 0,61% | US$ 1,86M | 2026-03-31 |
| BIOS Fund III NT, LP | Institution | 450 811 | 0,55% | US$ 1,68M | 2026-05-12 |
| BIOS Fund III, LP | Institution | 430 665 | 0,53% | US$ 1,60M | 2026-05-12 |
| Columbia Management Investment Advisers, LLC | Institution | 388 491 | 0,48% | US$ 1,45M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 326 809 | 0,40% | US$ 1,22M | 2026-03-31 |
| Great Point Partners, LLC | Institution | 324 340 | 0,40% | US$ 1,21M | 2026-03-31 |
| Mr. Richard Rodgers | Initiés | 318 655 | 0,39% | US$ 1,19M | 2026-04-20 |
| Mr. Sean Ainsworth | Initiés | 297 325 | 0,37% | US$ 1,11M | 2026-04-20 |
| Dr. James S. Manuso | Initiés | 292 951 | 0,36% | US$ 1,09M | 2026-04-20 |
| Vanguard Fiduciary Trust Company | Institution | 281 801 | 0,35% | US$ 1,05M | 2026-03-31 |
| UBS Asset Management AG | Institution | 257 649 | 0,32% | US$ 958,45k | 2026-03-31 |
| Dr. Jean Bennett | Initiés | 234 652 | 0,29% | US$ 872,91k | 2026-04-20 |
| Ms. Susan Benton | Initiés | 219 527 | 0,27% | US$ 816,64k | 2026-04-20 |
| State Street Global Advisors, Inc. | Institution | 199 953 | 0,25% | US$ 743,83k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 158 103 | 0,19% | US$ 588,14k | 2026-03-31 |
| BlackRock, Inc. | Institution | 147 740 | 0,18% | US$ 549,59k | 2026-03-31 |
| Voleon Capital Management LP | Institution | 143 796 | 0,18% | US$ 534,92k | 2026-03-31 |
| Seven Fleet Capital Management LP | Institution | 134 242 | 0,16% | US$ 499,38k | 2026-03-31 |
Les dernières valeurs consultées apparaîtront dans cette boîte, vous permettant de choisir facilement les titres vus auparavant.
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