Rapport Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of small molecule medicines for patients suffering from central nervous system (CNS) disorders. Its lead product candidate is receptor associated protein (RAP)-219, an investigational sma... Rapport Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of small molecule medicines for patients suffering from central nervous system (CNS) disorders. Its lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. The company also develops RAP-199, a TARPy8 targeted molecule with differentiated chemical and pharmacokinetic properties; and nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and a9a10 nAChR for the treatment of hearing disorders. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts. Show more
BOSTON and SAN DIEGO, Jan. 09, 2025 (GLOBE NEWSWIRE) -- In a release issued under the same headline earlier today by Rapport Therapeutics, Inc. (Nasdaq: RAPP), please note the references to the...
In the PET trial, RAP-219 achieved and exceeded target receptor occupancy, increasing support for the dosing regimen utilized in the ongoing Phase 2a trial in focal epilepsy; restricted...
A 30% reduction in long episodes was shown to be associated with a 50% or greater reduction in clinical seizures in a post-hoc analysis, validating the biomarker for proof-of-concept studies...
BOSTON and SAN DIEGO, Nov. 14, 2024 (GLOBE NEWSWIRE) -- Rapport Therapeutics, Inc. (Nasdaq: RAPP), a clinical-stage biotechnology company dedicated to the discovery and development of small...
Période | Variation | Variation % | Ouver. | Haut | Bas | Moyenne Vol. Quot. | VWAP | |
---|---|---|---|---|---|---|---|---|
1 | 4.165 | 30.6024981631 | 13.61 | 18 | 13.13 | 102880 | 16.11342639 | CS |
4 | -0.225 | -1.25 | 18 | 18.25 | 12.0948 | 104434 | 14.73374576 | CS |
12 | -8.745 | -32.9751131222 | 26.52 | 27.26 | 12.0948 | 114321 | 18.70997641 | CS |
26 | -3.225 | -15.3571428571 | 21 | 29.74 | 12.0948 | 130539 | 20.45765534 | CS |
52 | -0.225 | -1.25 | 18 | 29.74 | 12.0948 | 148079 | 21.33485389 | CS |
156 | -0.225 | -1.25 | 18 | 29.74 | 12.0948 | 148079 | 21.33485389 | CS |
260 | -0.225 | -1.25 | 18 | 29.74 | 12.0948 | 148079 | 21.33485389 | CS |
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