FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

FRIEDMAN RICHARD H 		2. Issuer Name and Ticker or Trading Symbol

BioScrip, Inc. [ BIOS ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
Chairman of the Board and CEO
(Last)          (First)          (Middle)

100 CLEARBROOK ROAD 		3. Date of Earliest Transaction (MM/DD/YYYY)

11/13/2009
(Street)

ELMSFORD, NY 10523
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, $.0001 Par Value   11/13/2009     M    100   A $5.80   1019512   D    
Common Stock, $.0001 Par Value   11/13/2009     S    100   D $9.00   1019412   D    
Common Stock, $.0001 Par Value   11/16/2009     M    8202   A $5.80   1027614   D    
Common Stock, $.0001 Par Value   11/16/2009     S    8202   D $9.004   (1) 1019412   D    
Common Stock, $.0001 Par Value                  10000   I   By Shares Held By Ltd Partnership   (2)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (Right to Buy)   $5.80   11/13/2009     M         100    1/2/2004   (3) 1/2/2013   Common Stock, $.0001 Par Value   100   $0   119900   D    
Employee Stock Option (Right to Buy)   $5.80   11/16/2009     M         8202    1/2/2004   (3) 1/2/2013   Common Stock, $.0001 Par Value   8202   $0   111698   D    
Employee Stock Option (Right to Buy)   $12.20                    11/28/2002   (3) 11/28/2011   Common Stock, $.0001 Par Value   200000     200000   D    
Employee Stock Option (Right to Buy)   $17.80                    1/2/2003   (3) 1/2/2012   Common Stock, $.0001 Par Value   200000     200000   D    
Employee Stock Option (Right to Buy)   $7.03                    1/2/2005   (3) 1/2/2014   Common Stock, $.0001 Par Value   200000     200000   D    
Employee Stock Option (Right to Buy)   $6.36                    1/3/2006   (3) 1/3/2015   Common Stock, $.0001 Par Value   200000     200000   D    
Employee Stock Option (Right to Buy)   $7.54                    1/3/2007   (3) 1/3/2016   Common Stock, $.0001 Par Value   200000     200000   D    
Employee Stock Option (Right to Buy)   $3.46                    1/2/2008   (4) 1/2/2017   Common Stock, $.0001 Par Value   66667     66667   D    
Employee Stock Option (Right to Buy)   $7.70                    1/2/2009   (4) 1/2/2018   Common Stock, $.0001 Par Value   130000     130000   D    
Employee Stock Option (Right to Buy)   $7.70                    1/2/2009   (4) 1/2/2018   Common Stock, $.0001 Par Value   70000     70000   D    
Option To Purchase Common Stock   $6.52                    4/29/2009   (4) 4/29/2018   Common Stock, $.0001 Par Value   112500     112500   D    
Option To Purchase Common Stock   $2.73                    4/28/2010   (4) 4/28/2019   Common Stock, $.0001 Par Value   150000     150000   D    

Explanation of Responses:
( 1)  Shares were sold at various prices between $9.00 and $9.03 per share. The reporting person undertakes to provide (upon request by the SEC staff, the issuer, or a security holder of the issuer) full information regarding the number of shares purchased or sold at each separate price.
( 2)  Shares of Common Stock are owned by the Richard Friedman Family Limited Partnership, of which Mr. Friedman is a general and limited partner. Mr. Friedman has shared voting and dispositive power with respect to these shares of Common Stock.
( 3)  Fully Vested
( 4)  Vests and becomes exercisable in three equal annual installments commencing on the first anniversary of the date of grant.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
FRIEDMAN RICHARD H
100 CLEARBROOK ROAD
ELMSFORD, NY 10523 		X
Chairman of the Board and CEO

Signatures
/s/ Richard H. Friedman 11/17/2009
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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