TIDMSAR

RNS Number : 8299S

Sareum Holdings PLC

08 November 2023

Sareum Holdings PLC

("Sareum" or the "Company")

Director Dealings

Cambridge, UK, 8 November 2023 - Sareum Holdings plc (AIM: SAR), a biotechnology company developing next generation kinase inhibitors for autoimmune disease and cancer, announces the following share transactions carried out by Directors.

As announced on 2 November 2023, Dr Tim Mitchell, Chief Executive Officer, and Dr John Reader, Chief Scientific Officer, each exercised options over 95,040 ordinary shares of 1.25 pence each in the Company (the "Options Exercise"), at an exercise price of 30 pence per ordinary share.

Of those shares received pursuant to the Options Exercise, Dr Mitchell and Dr Reader have retained 23,040 and 44,614 ordinary shares, respectively, following the sale of 72,000 and 50,426 ordinary shares, respectively, at a price of 56.8 pence per ordinary share (the "Share Sales"). The Share Sales were undertaken partly in order to compensate for the cost and tax liabilities arising from the Options Exercise.

Following the Options Exercise and Share Sales, Dr Mitchell's and Dr Reader's resultant interests in the Company will be as follows:

 
 Director/                Number of         Number of      Sale         Resultant       Percentage 
  PDMR             shares purchased       shares sold     price      total number        of issued 
                        pursuant to          pursuant                 of ordinary    share capital 
                        the Options    to Sale Shares                 shares held 
                           Exercise                                in the Company 
 T im Mitchell 
  (1)                        95,040            72,000     56.8p         1,032,561            1.47% 
                 ------------------  ----------------  --------  ----------------  --------------- 
 J ohn Reader 
  (2)                        95,040            50,426     56.8p         1,077,111            1.53% 
                 ------------------  ----------------  --------  ----------------  --------------- 
 

(1) - Included within Tim Mitchell's total holding are 200,000 ordinary shares held by his spouse.

(2) - Included withing John Reader's total holding are 66,666 ordinary shares held by his spouse.

For further information, please contact:

 
 Sareum Holdings plc 
  Tim Mitchell, CEO                                01223 497700 
  Lauren Williams, Head of Investor Relations      ir@sareum.co.uk 
 Strand Hanson Limited (Nominated Adviser) 
  James Dance / James Bellman                      020 7409 3494 
 Peel Hunt LLP (Joint Corporate Broker) 
  James Steel / Patrick Birkholm                   020 7418 8900 
 Hybridan LLP (Joint Corporate Broker) 
  Claire Noyce 
                                                   020 3764 2341 
  ICR Consilium (Financial PR) 
  Jessica Hodgson / Davide Salvi / Stella 
  Lempidaki                                        020 3709 5700 
 

PDMR Notification Forms

The information set out below is provided in accordance with the requirements of Article 19(3) of the EU Market Abuse Regulation No 596/2014.

 
 1.   Details of the person discharging managerial responsibilities 
       / person closely associated 
 a)   Name                              Tim Mitchell 
     --------------------------------  -------------------------------------------- 
 2.   Reason for the Notification 
     ------------------------------------------------------------------------------ 
 a)   Position/status                   Chief Executive Officer 
     --------------------------------  -------------------------------------------- 
 b)   Initial notification/amendment    Initial notification 
     --------------------------------  -------------------------------------------- 
 3.   Details of the issuer, emission allowance market participant, 
       auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------------ 
 a)   Name                              SAREUM HOLDINGS PLC 
     --------------------------------  -------------------------------------------- 
 b)   LEI                               213800PKERN2DY8FFM72 
     --------------------------------  -------------------------------------------- 
 4.   Details of the transaction(s): section to be repeated for 
       (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv)each place where transactions have 
       been conducted 
     ------------------------------------------------------------------------------ 
 a)   Description of the Financial      Ordinary shares of 1.25p each in the 
       instrument, type of instrument    share capital of Sareum Holdings plc 
     --------------------------------  -------------------------------------------- 
      Identification code               ISIN for Ordinary Shares: GB00B02RFS12 
     --------------------------------  -------------------------------------------- 
 b)   Nature of the Transaction         Sale of ordinary shares 
     --------------------------------  -------------------------------------------- 
 c)   Price(s) and volume(s)             Price(s)           Volume(s) 
                                                     56.8p              72,000 sold 
                                                            ----------------------- 
     --------------------------------  -------------------------------------------- 
 d)        Aggregated information        Price(s)           Volume(s) 
             *    Aggregated volume                  56.8p              72,000 sold 
                                                            ----------------------- 
 
             *    Price 
     --------------------------------  -------------------------------------------- 
 e)   Date of the transaction           7 November 2023 
     --------------------------------  -------------------------------------------- 
 f)   Place of the transaction          London Stock Exchange (AIM) 
     --------------------------------  -------------------------------------------- 
 
 
 1.   Details of the person discharging managerial responsibilities 
       / person closely associated 
 a)   Name                              John Reader 
     --------------------------------  -------------------------------------------- 
 2.   Reason for the Notification 
     ------------------------------------------------------------------------------ 
 a)   Position/status                   Chief Scientific Officer 
     --------------------------------  -------------------------------------------- 
 b)   Initial notification/amendment    Initial notification 
     --------------------------------  -------------------------------------------- 
 3.   Details of the issuer, emission allowance market participant, 
       auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------------ 
 a)   Name                              SAREUM HOLDINGS PLC 
     --------------------------------  -------------------------------------------- 
 b)   LEI                               213800PKERN2DY8FFM72 
     --------------------------------  -------------------------------------------- 
 4.   Details of the transaction(s): section to be repeated for 
       (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv)each place where transactions have 
       been conducted 
     ------------------------------------------------------------------------------ 
 a)   Description of the Financial      Ordinary shares of 0.025p each in 
       instrument, type of instrument    the share capital of Sareum Holdings 
                                         plc 
     --------------------------------  -------------------------------------------- 
      Identification code               ISIN for Ordinary Shares: GB00B02RFS12 
     --------------------------------  -------------------------------------------- 
 b)   Nature of the Transaction         Sale of ordinary shares 
     --------------------------------  -------------------------------------------- 
 c)   Price(s) and volume(s)             Price(s)           Volume(s) 
                                                     56.8p              50,426 sold 
                                                            ----------------------- 
     --------------------------------  -------------------------------------------- 
 d)        Aggregated information        Price(s)           Volume(s) 
             *    Aggregated volume                  56.8p              50,426 sold 
                                                            ----------------------- 
 
             *    Price 
     --------------------------------  -------------------------------------------- 
 e)   Date of the transaction           7 November 2023 
     --------------------------------  -------------------------------------------- 
 f)   Place of the transaction          London Stock Exchange (AIM) 
     --------------------------------  -------------------------------------------- 
 

About Sareum

Sareum Holdings (AIM:SAR) is a clinical-stage biotechnology company developing next generation kinase inhibitors for autoimmune disease and cancer.

The Company is focused on developing next generation small molecules which modify the activity of the JAK kinase family and have best-in-class potential. Its lead candidate, SDC-1801, simultaneously inhibits TYK2 and JAK1. SDC-1801 is a potential treatment for a range of autoimmune diseases and has entered Phase 1a/b clinical development with an initial focus on psoriasis.

Sareum has an economic interest in SRA737, a clinical-stage Chk1 inhibitor which it originally developed in collaboration with several Cancer Research UK-related organisations. SRA737 has shown promising safety and efficacy in two Phase 1/2 clinical trials.

Sareum is also developing SDC-1802, a TYK2/JAK1 inhibitor with a potential application for cancer immunotherapy.

Sareum Holdings plc is based in Cambridge, UK, and is listed on the AIM market of the London Stock Exchange, trading under the ticker SAR. For further information, please visit the Company's website at www.sareum.com

- Ends -

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