FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

FRIEDMAN RICHARD H 		2. Issuer Name and Ticker or Trading Symbol

BioScrip, Inc. [ BIOS ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

100 CLEARBROOK ROAD 		3. Date of Earliest Transaction (MM/DD/YYYY)

3/1/2012
(Street)

ELMSFORD, NY 10523
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, $.0001 Par Value   3/1/2012   (3)   M    20000   A $2.73   302779   D   (2)  
Common Stock, $.0001 Par Value   3/1/2012     S    20000   D $6.4017   (4) 282779   D   (2)  
Common Stock, $.0001 Par Value                  250000   I   By The Richard H. Friedman Grantor Retained Annuity Trust   (5)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option To Purchase Common Stock   $2.73   3/1/2012   (3)   M         20000    4/28/2010   (1) 5/31/2012   Common Stock, $.0001 Par Value   0   $ 0   10000   D    
Employee Stock Option (Right to Buy)   $5.8                    1/2/2004   5/31/2012   Common Stock, $.0001 Par Value   91698     91698   D    
Employee Stock Option (Right to Buy)   $7.03                    1/2/2005   (6) 5/31/2012   Common Stock, $.0001 Par Value   200000     200000   D    
Employee Stock Option (Right to Buy)   $6.36                    1/3/2006   (6) 5/31/2012   Common Stock, $.0001 Par Value   200000     200000   D    
Employee Stock Option (Right to Buy)   $7.54                    1/3/2007   (6) 5/31/2012   Common Stock, $.0001 Par Value   200000     200000   D    
Employee Stock Option (Right to Buy)   $3.46                    1/2/2008   (1) 5/31/2012   Common Stock, $.0001 Par Value   66667     66667   D    
Employee Stock Option (Right to Buy)   $7.7                    1/2/2009   (1) 5/31/2012   Common Stock, $.0001 Par Value   130000     130000   D    
Employee Stock Option (Right to Buy)   $7.7                    1/2/2009   (1) 5/31/2012   Common Stock, $.0001 Par Value   70000     70000   D    
Option To Purchase Common Stock   $6.52                    4/29/2009   (1) 5/31/2012   Common Stock, $.0001 Par Value   112500     112500   D    

Explanation of Responses:
( 1)  Vests and becomes exercisable in three equal annual installments commencing on the first anniversary of the date of grant.
( 2)  Includes 10,000 shares owned jointly with Mr. Friedman's spouse.
( 3)  These sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 15, 2011.
( 4)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.33 to $6.40, inclusive. The reporting person undertakes to provide BioScrip, Inc., any security holder of BioScrip, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.
( 5)  Shares of Common Stock are owned by the Richard H. Friedman Grantor Retained Annuity Trust dated June 22, 2009. The 250,000 shares held in the trust were transferred to the trust by Mr. Friedman on June 22, 2009. Mr. Friedman is trustee of the trust and has sole voting and dispositive power with respect to these shares of Common Stock.
( 6)  Fully Vested

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
FRIEDMAN RICHARD H
100 CLEARBROOK ROAD
ELMSFORD, NY 10523 		X



Signatures
/s/ Richard H. Friedman 3/5/2012
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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