ASLAN Pharmaceuticals to Present Data on ASLAN004 at Society for Investigative Dermatology
05 Mai 2021 - 11:22AM
ASLAN Pharmaceuticals (NASDAQ: ASLN), a clinical-stage immunology
focused biopharmaceutical company developing innovative treatments
to transform the lives of patients, today announced that an
abstract on ASLAN004 has been accepted for poster presentation at
the upcoming 2021 Society for Investigative Dermatology (SID)
virtual meeting between 3-8 May, 2021. The data is available to
view during the Pharmacology and Drug Development segment on 6 May,
2.30pm to 4pm EST, and will be published in the fall edition of the
Journal of Investigative Dermatology.
The late-breaking abstract accepted for poster presentation
(Abstract #LB793), titled “A phase 1, open-label, single ascending
dose study in healthy subjects of the safety, tolerability and
pharmacokinetics of ASLAN004, a novel IgG anti-IL-13 receptor alpha
1 Inhibitor”, will be presented by Dr Lawrence Soon-U Lee, first
author of the abstract. Other authors of the SAD abstract include
Dr Hartina Hajireen from the Clinical Trials & Research Unit,
Changi General Hospital, and Dr Alison Ward, from ASLAN
Pharmaceuticals. ASLAN004 is a novel, fully human monoclonal
antibody that targets the IL-13 receptor α1 subunit, or IL-13Rα1,
with potential to be a first-in-class therapy for atopic dermatitis
and asthma. During the SID meeting, new data will be presented from
the Single Ascending Dose (SAD) healthy volunteer study, completed
in 2019, that demonstrated ASLAN004’s favourable tolerability
profile as an IL-13Rα1 inhibitor and as a differentiated treatment
method for atopic dermatitis patients. The SAD data readout
supported ASLAN’s decision to initiate the ongoing, phase 1b
Multiple Ascending Dose (MAD) study of ASLAN004.
The poster will be available to view online in the news and
publications section of the ASLAN website at 2:30pm ET, 2:30am SGT.
http://aslanpharma.com/news/All presentations from the event will
be available to view on demand until 31 May. More information on
the presentations available during the event can be found here:
https://www.sidannualmeeting.org/information/meeting-program-attendee-user-guide/.
Media and IR contacts
Emma ThompsonSpurwing CommunicationsTel: +65 6571
2021Email: ASLAN@spurwingcomms.com |
Robert UhlWestwicke PartnersTel: +1 858 356
5932Email: robert.uhl@westwicke.com |
About ASLAN Pharmaceuticals
ASLAN Pharmaceuticals (Nasdaq:ASLN) is a clinical-stage
immunology focused biopharmaceutical company developing innovative
treatments to transform the lives of patients. Led by a senior
management team with extensive experience in global development and
commercialisation, ASLAN has a clinical portfolio comprised of a
first-in-class monoclonal therapy, ASLAN004, that is being
developed in atopic dermatitis and other immunology indications,
and ASLAN003, which it plans to develop for autoimmune disease. For
additional information please visit www.aslanpharma.com
About ASLAN004 ASLAN004 is a potential
first-in-class human monoclonal antibody that binds to the IL-13
receptor α1 subunit (IL13Rα1), blocking signalling of two
pro-inflammatory cytokines, IL-4 and IL-13, which are central to
triggering symptoms of atopic dermatitis (AD), such as redness and
itching of the skin. AD is a chronic, inflammatory skin condition
which severely impacts quality of life for millions of children and
adults globally. ASLAN004 is the only IL13Rα1 receptor in clinical
development for the treatment of AD.
Forward looking statements This release and the
accompanying financial information, if any, contains
forward-looking statements. These statements are based on the
current beliefs and expectations of the management of ASLAN
Pharmaceuticals Limited and/or its affiliates (the "Company").
These forward-looking statements may include, but are not limited
to, statements regarding the Company’s business strategy and
clinical development plans; the Company’s plans to develop and
commercialise ASLAN004 and ASLAN003; the safety and efficacy of
ASLAN004 and ASLAN003; the Company’s plans and expected timing with
respect to clinical trials and clinical trial results for ASLAN004
and ASLAN003; the Company’s plans and expected timing with respect
to regulatory filings and approvals, and the size and growth
potential of the markets for ASLAN004 and ASLAN003; the potential
for ASLAN004 as a novel, first-in class antibody targeting IL-13R
with a differentiated efficacy and safety profile in atopic
dermatitis; and the Company’s belief that its cash and cash
equivalents will be sufficient to fund operations into 2023. The
Company’s estimates, projections and other forward-looking
statements are based on management's current assumptions and
expectations of future events and trends, which affect or may
affect the Company’s business, strategy, operations or financial
performance, and inherently involve significant known and unknown
risks and uncertainties. Actual results and the timing of events
could differ materially from those anticipated in such
forward-looking statements as a result of many risks and
uncertainties, which include, unexpected safety or efficacy data
observed during preclinical or clinical studies; clinical site
activation rates or clinical trial enrolment rates that are lower
than expected; the impact of the COVID-19 pandemic on the Company’s
business and the global economy; general market conditions; changes
in the competitive landscape; and the Company’s ability to obtain
sufficient financing to fund its strategic and clinical development
plans. Other factors that may cause actual results to differ from
those expressed or implied in such forward-looking statements are
described in the Company’s US Securities and Exchange Commission
filings and reports (Commission File No. 001-38475), including the
Company’s Annual Report on Form 20-F filed with the US Securities
and Exchange Commission on April 16, 2020. All statements other
than statements of historical fact are forward-looking statements.
The words “believe,” “may,” “might,” “could,” “will,” “aim,”
“estimate,” “continue,” “anticipate,” “intend,” “expect,” “plan,”
or the negative of those terms, and similar expressions that convey
uncertainty of future events or outcomes are intended to identify
estimates, projections and other forward-looking statements.
Estimates, projections and other forward-looking statements speak
only as of the date they were made, and, except to the extent
required by law, the Company undertakes no obligation to update or
review any estimate, projection or forward-looking statement.
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