IMI's LungAlert(TM) test may be useful as initial lung cancer screening test
24 Mai 2004 - 7:00PM
PR Newswire (US)
IMI's LungAlert(TM) test may be useful as initial lung cancer
screening test New Clinical Data Presented at the 100th American
Thoracic Society Meeting TORONTO, May 24 /PRNewswire-FirstCall/ --
A scientific abstract featuring IMI International Medical
Innovations Inc.'s (TSX:IMI, Amex: IME) unique and patented lung
cancer-screening test, LungAlert, was presented today at the
American Thoracic Society (ATS) international annual conference in
Orlando, Florida. The abstract presented was Examination of the
Association of Galactose Oxidase Reactivity in Sputum with Lung
Cancer, co-authored by Dr. John Miller and Dr. Gerard Cox of St.
Joseph's Healthcare Hamilton in Ontario, Canada. "This study data
will help generate further awareness and discussion of LungAlert as
a promising new approach to screening for lung cancer," said Dr.
Brent Norton, IMI President and CEO. "The key challenge in treating
lung cancer is to identify the disease in the earliest possible
stage. Lung cancer is the leading cause of cancer deaths and there
is currently no simple, widely available screening test. We believe
these study results are encouraging and confirm the potential of
our approach." "A majority of lung cancers occur in current and
former smokers," said Dr. John Miller, Head of Thoracic Surgery at
McMaster University and co-lead investigator of the study with Dr.
Gerard Cox. "Because no other options currently exist to screen for
early-stage lung cancer, we are very encouraged by the results we
have seen in this and earlier studies with LungAlert." The findings
of this ongoing study, which support the data presented by Drs. Cox
and Miller at the 2003 American Association of Cancer Research
(AACR) annual meeting, show that LungAlert's reactivity in sputum
samples may be useful as an initial screening test to identify
high-risk subjects who would benefit from other tests, such as
spiral computed tomography. Patients with cancer had significantly
higher values than those who did not. The majority of these
patients had early-stage disease where surgery for cure is a
possibility. This study, which examined 122 subjects, is part of a
500-patient clinical trial at St. Joseph's Hospital and McMaster
University, Hamilton, Ontario. The clinical trial is designed to
determine LungAlert values in individuals with lung cancer, in
individuals with benign lung disease and in healthy smokers. In the
interim data presented in 2003, LungAlert showed high sensitivity
for lung cancer. LungAlert is a non-invasive test that detects a
cancer-associated sugar in a sputum (phlegm) sample. The patient
produces the sputum by coughing into a cup. The sample is treated
with IMI's proprietary test, which produces a color change reaction
that is read with a color reader to quantify the results. Lung
cancer is the number one cause of cancer-related death for both men
and women in North America, with 179,000 deaths expected in
2004.(1) Lung cancer causes more deaths than any other cancer.
According to the American Cancer Society, only 16% of lung cancers
are diagnosed at an early, localized stage. More than 85% of lung
cancer cases can be directly or partly attributed to smoking.(2)
Worldwide, one in three adults over age 15, or 1.1 billion people,
are smokers.(3) The American Thoracic Society annual conference
attracts 14,000 delegates and is the premier international forum
for physicians and scientists who work in pulmonary and critical
care medicine. (1) Data compiled from American Cancer Society,
Cancer Facts and Figures, 2004; Canadian Cancer Society, 2004
Update. (2) American Lung Association. (3) The World Bank Group -
Economics of Tobacco Control, Curbing the Epidemic, 1999. About IMI
IMI is a world leader in predictive medicine, dedicated to
developing rapid, non-invasive tests for the early detection of
life-threatening diseases, particularly cardiovascular disease and
cancer. The company's head office is located in Toronto, and its
research and product development facility is at McMaster University
in Hamilton, Ontario. For further information, please visit the
company's website at http://www.imimedical.com/. This release
contains forward-looking statements that reflect the company's
current expectations regarding future events. The forward-looking
statements involve risks and uncertainties. Actual events could
differ materially from those projected herein and depend on a
number of factors including, but not limited to, changing market
conditions, successful and timely completion of clinical studies,
uncertainties related to the regulatory approval process,
establishment of corporate alliances and other risks detailed from
time to time in the company's quarterly, annual and other regular
filings. DATASOURCE: IMI International Medical Innovations Inc.
CONTACT: Sarah Borg-Olivier, Director, Communications, (416)
222-3449,
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