FluoroPharma Announces Milestone for BFPET
26 Juillet 2012 - 7:23PM
FluoroPharma Medical, Inc. (OTCBB:FPMI), a company specializing in
the development of novel diagnostic imaging products that utilize
positron emission tomography (PET) technology for the detection and
assessment of disease before clinical manifestation, today
announced that they have received high quality images in an
investigator-sponsored clinical trial in China where patients with
CAD were given BFPET, its imaging agent for measuring
cardiovascular blood flow. This is most encouraging as the company
is starting phase II trials.
Patients are being imaged at the PLA 301 hospital in Beijing
where the images give a direct comparison between stress perfusion
imaging using sestamibi and BFPET. According to Dr. Alan Fischman,
former head of nuclear medicine at Massachusetts General Hospital
and the principal investigator of the BFPET phase I trial, "initial
results are impressive. Image quality obtained using PET is superb.
BFPET shows clear diagnostic qualities as well as increased
resolution, inherent in PET. The initial images look spectacular
and we are confident that when all the patients are imaged, the
data will further support clinical development of the agent."
Approximately 20 patients are expected to be imaged with this
investigator-initiated study concluding by the beginning of the 4th
quarter of 2012.
"These images mark a milestone for BFPET and this exciting
technology; bringing it a step closer to the world's medical
community. We firmly believe, however, that the true beneficiaries
of imaging agents like BFPET will be patients as it offers the
potential for non-invasive diagnostic images with higher
specificity. This will provide early and more accurate information
to enable more effective patient management decisions," commented
Thijs Spoor, FluoroPharma's President and Chief Executive Officer.
"Today's announcement supports our earlier findings and increases
our confidence that the images we observed in Phase I will be
reproduced in Phase II. It also validates the importance and value
of FluoroPharma's technology in important growth markets where
diagnostic imaging is playing an increasingly significant role in
the early detection of disease," he added.
About BFPET: Myocardial Perfusion Imaging
FluoroPharma's BFPET is a novel imaging agent for myocardial
perfusion imaging with the potential for measuring cardiovascular
blood flow. BFPET, a Flourine-18 labeled tracer, has been designed
to enter the myocardial cells in direct proportion to blood flow
and cell membrane potential. These are two of the most important
physiological indicators upon which adequate blood supply to the
heart depends. BFPET has been designed to differentiate among those
cells of the myocardium that may be ischemic, infarcted and those
that are healthy.
Ischemic and infarcted cells should take up less BFPET than
healthy myocardial cells. The signal emitted by BFPET should be
inversely proportional to the extent of myocardial injury.
Therefore, FluoroPharma believes that ischemic heart tissue can be
reliably detected by using BFPET
Late last year, FluoroPharma announced that it had been granted
patent rights in China for BFPET and another imaging agent, AZPET
which is still in the very early phase of discovery.
About Symptomatic coronary artery disease (CAD)
Symptomatic coronary artery disease (CAD) affects millions of
patients worldwide and, according to the World Health Organization,
cardiovascular diseases are the leading causes of death and
disability in the world. Cardiologists' demand for faster, more
accurate diagnostic tools continuously drives the development of
non-invasive techniques with increased sensitivity and accuracy for
the detection and assessment of acute and chronic CAD
About FluoroPharma Medical FluoroPharma is a
biopharmaceutical company engaged in the discovery and development
of proprietary PET imaging products to evaluate cardiac disease at
the cellular and molecular levels. The Company has licensed
technology from the Massachusetts General Hospital in Boston.
The Company's goal is to enable personalized medicine through
advanced imaging products that will help the medical community
diagnose disease more accurately at the earliest stages, leading to
more effective treatment, management and better patient
outcomes.
The Company's initial focus is the development of breakthrough
positron emission tomography (PET) imaging agents for the efficient
detection and assessment of acute and chronic forms of coronary
artery disease (CAD). FluoroPharma is advancing two products in
clinical trials for assessment of acute and chronic forms of
coronary disease. These first in class agents have been designed to
rapidly target myocardial cells. Other products in development
include agents for detection of inflamed atherosclerotic plaque in
peripheral arteries, agents with the potential to image Alzheimer's
disease and agents that could potentially be used for imaging
specific cancers.
In addition to the United States, Europe and China, patents
related to FluoroPharma's portfolio of imaging compounds have been
issued in Japan, Canada, Australia, Finland, Portugal, Ireland and
Mexico.
For more information on the Company, please visit:
www.fluoropharma.com
Forward-Looking Statements Except for
historical information contained herein, the statements in this
release are forward-looking. Forward-looking statements are
inherently unreliable and actual results may differ materially.
Examples of forward looking statements in this news release include
statements regarding FluoroPharma's research and development
activities and anticipated operating results. Factors which could
cause actual results to differ materially from these
forward-looking statements include such factors as significant
fluctuations in expenses associated with clinical trials, failure
to secure additional financing, the inability to complete
regulatory filings with the Food and Drug Administration, the
introduction of competing products, or management's ability to
attract and maintain qualified personnel necessary for the
development and commercialization of its planned products, and
other information that may be detailed from time to time in
FluoroPharma's filings with the United States Securities and
Exchange Commission. FluoroPharma undertakes no obligation to
publicly update or revise any forward-looking statements, whether
as a result of new information, future events or otherwise.
CONTACT: Carol J. Perlman
cperlman@fluoropharma.com
917-592-9260
FluoroPharma Medical (CE) (USOTC:FPMI)
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