News Summary:
- Waters Xevo™ MRT Mass Spectrometer employs next-generation
multi-reflecting time-of-flight technology to deliver class-leading
combination of high resolution and speed without compromising
analytical performance.i
- Delivers up to 6x resolution at maximum speed and up to 2x mass
accuracy of competitive systems,ii enabling scientists
to process more samples in less time for large-cohort biomedical
research and epidemiology-type studies.
- Complete workflows available for metabolomic, lipidomic, and
metabolite identification enables customer flexibility and
convenience using Waters™ software, columns, and instruments for
high throughput separations, and universal data-sharing with
third-party software applications.
ANAHEIM,
Calif., and MILFORD,
Mass., June 3, 2024 /PRNewswire/
-- 72nd ASMS Conference on Mass Spectrometry and
Allied Topics – Waters Corporation (NYSE: WAT) today unveiled the
Xevo™ MRT, its highest-performing benchtop mass spectrometer (MS),
setting new standards for delivering high resolution and speed,
critical for large population and epidemiology-type studies. It
builds on the innovative technology pioneered by the Waters SELECT
SERIES™ MRT MS. The new Xevo MRT MS combines the raw power and
resolution speed of multi-reflecting time-of-flight (MRT) and
hybrid quadrupole time-of-flight (QTof) technologies within a
flexible benchtop platform.
Laboratory products that obtain the ACT
Ecolabel make it easier for scientists to make more sustainable
choices.
"Understanding complex diseases requires analysis of thousands
of samples from large human cohorts to provide statistically valid
studies. This puts increased pressure on drug discovery scientists
to deliver high-quality data in shorter run times," said Dr.
Udit Batra, CEO and President of
Waters Corporation. "The Xevo MRT mass spectrometer is a next
generation QTof built from the ground up to address this unmet
need, delivering high resolution and speed without compromising
analytical performance. Its multi-reflecting time-of-flight design
enables simultaneous high sensitivity, high resolution, and speed
in a small footprint, accelerating time-to-results and ensuring
high-quality experimental outcomes."
The Xevo MRT system delivers a class-leadingiii
100,000 full width half maximum (FWHM) resolution at 100 Hz MS/MS
scan speed and <500 parts per billion (ppb) mass accuracy. This
enables deeper probing of biologically relevant concentrations with
high levels of mass accuracy, independent of acquisition rate.
"A range of mass spec approaches are available for metabolomic,
lipidomic, and metabolite identification studies, yet all require
compromises to be made - either in data quality or analytical
efficiency," said Professor Perdita
Barran, Chair of Mass Spectroscopy in the University of
Manchester (UK) Department of
Chemistry and Director of the Michael Barber Centre for
Collaborative Mass Spectrometry at the Manchester Institute of
Biotechnology. "The Xevo MRT MS is impressive technology capable of
higher sample throughput combined with extremely high precision,
which can significantly advance target validation and phenotyping
studies. The increase in scan speed and data quality are critical
as it can allow us to run more samples in less time without
compromising confidence in our data and we are very excited by how
this is allowing us to accelerate the development of a diagnostic
test for Parkinson's Disease."
The innovative multi-reflecting time-of-flight design of the
Xevo MRT MS offers scientists the power to work at maximum
resolution with high sensitivity and fast data acquisition rates.
This helps ensure confident identification of analytes across a
range of samples and complex matrices and generate comprehensive
and highly accurate mass data for scientific interpretation.
Waters offers complete workflows for metabolomic, lipidomic, and
metabolite identification for the Xevo MRT MS, alongside Waters
high throughput ACQUITY™ UPLC™ Systems and UPLC Column chemistries
and waters_connect™ Software for data acquisition, processing, and
reporting. The system supports universal data-sharing via mzML file
formats with third-party informatics software, including popular
applications from Mass Analytica™ such as its MARS, Lipostar2,
and MassMetaSite software offerings.
The Waters Xevo MRT MS is orderable today for shipment in the
second half of 2024.
Additional Resources
- Learn more at www.waters.com/XevoMRT
- View the Waters ASMS 2024 Online Press Kit for downloadable
product photos, spec sheets, infographics and videos.
- Read the solution brief: "A High-Throughput Lipidomic
Workflow Using the Waters Xevo MRT Mass Spectrometer"
- Follow and connect with Waters via LinkedIn, Twitter, and
Facebook
About Waters Corporation (www.waters.com)
Waters Corporation (NYSE: WAT), a global leader in
analytical instruments and software, has pioneered chromatography,
mass spectrometry, and thermal analysis innovations serving the
life, materials, food, and environmental sciences for more than 65
years. With approximately 7,700 employees worldwide, Waters
operates directly in 35 countries, including 15 manufacturing
facilities, and with products available in more than 100
countries.
Waters, Xevo, SELECT SERIES, ACQUITY, UPLC, and
waters_connect are trademarks of Waters Technologies Corporation.
Mass Analytica is a trademark of Mass Spec Analytica,
S.L.
Contact:
Janice Foley
Senior Public Relations Manager, Corporate Communications
Waters Corporation
janice_foley@waters.com
+1.617.823.5555
i Estimates based on Xevo MRT MS
performance comparison to competitor instruments @100Hz @m/z 956 =
100K FWHM and <500ppb mass
accuracy.
ii Xevo MRT MS Resolution of 100K FWHM @ m/z 956 is up to 1.5x to 6x
competitor instruments @100Hz; Xevo MRT Mass Accuracy of <500ppb
is 2x competitor systems @ 1ppm.
iii Xevo MRT MS Resolution of 100K FWHM @ m/z 956 is up to 1.5x to 6x
competitor instruments @100Hz; Xevo MRT Mass Accuracy of <500ppb
is 2x competitor systems @ 1ppm.
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SOURCE Waters Corporation